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首页> 外文期刊>Dermatologic surgery >Immediate pathologic effects on the vein wall of foam sclerotherapy.
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Immediate pathologic effects on the vein wall of foam sclerotherapy.

机译:泡沫硬化疗法对静脉壁的即时病理影响。

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摘要

BACKGROUND: During the past 10 years, sclerotherapy has radically changed, the foam sclerotherapy method being better than that of liquid sclerotherapy. OBJECTIVES: We have analyzed the immediate pathologic effects on the saphenous vein wall in vivo after sclerotherapy with sodium tetradecyl sulfate (STD) foam. METHODS: A group of six patients affected by chronic venous insufficiency, operated on by stripping of the saphenous vein, underwent an intraoperative procedure of sclerotherapy to an isolated but not yet removed tract of saphenous vein with 3% STD foam. RESULTS: The pathologic damage of the foam was extremely rapid with complete damage of the endothelium within the first 2 minutes. In the successive 15 and 30 minutes there was edema of the intimal with its progressive separation from the tunica media and the initial formation and adhesion of the thrombus to the tunica media. CONCLUSIONS: In this in vivo report we analyze the capacity of 3% STD foam sclerotherapy to damage the saphenous vein wall. The damage is extremely fast and shows the detachment of the intimal and the development of the microthrombus.
机译:背景:在过去的十年中,硬化疗法发生了根本性的变化,泡沫硬化疗法优于液体硬化疗法。目的:我们分析了十四烷基硫酸钠(STD)泡沫硬化疗法对体内大隐静脉壁的即时病理影响。方法:一组6例受慢性静脉功能不全影响的患者,通过切除隐静脉进行了术中巩膜治疗,术中使用了3%STD泡沫对分离但尚未切除的隐静脉进行了硬化治疗。结果:泡沫的病理损伤非常迅速,在最初的2分钟内内皮完全受损。在随后的15分钟和30分钟内,内膜水肿逐渐从中膜介质分离,血栓最初形成并粘附到中膜介质。结论:在本体内报告中,我们分析了3%STD泡沫硬化疗法损伤大隐静脉壁的能力。损伤非常快,显示出内膜的脱离和微血栓的发展。

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