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首页> 外文期刊>Diabetic medicine: A journal of the British Diabetic Association >The effects of total energy expenditure from all levels of physical activity vs. physical activity energy expenditure from moderate-to-vigorous activity on visceral fat and insulin sensitivity in obese Type 2 diabetic women.
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The effects of total energy expenditure from all levels of physical activity vs. physical activity energy expenditure from moderate-to-vigorous activity on visceral fat and insulin sensitivity in obese Type 2 diabetic women.

机译:在肥胖的2型糖尿病女性中,所有体育锻炼水平的总能量消耗与中度至剧烈运动的体育锻炼能量消耗对内脏脂肪和胰岛素敏感性的影响。

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AIMS: We examined the effects of physical activity with or without dietary restriction for 3 months on regional fat and insulin sensitivity and compared the effect of total energy expenditure from all levels of physical activity with that of physical activity energy expenditure from moderate-to-vigorous exercise in obese women with Type 2 diabetes. METHODS: In this randomized, controlled trial, we assessed change of body weight, abdominal visceral fat area, subcutaneous fat area and insulin sensitivity, expressed as K(ITT), and monitored total energy expenditure and physical activity energy expenditure using an accelerometer during a 12-week intervention in four groups: control, diet, exercise and diet plus exercise. RESULTS: The mean body mass index was 28.0 +/- 2.7 kg/m(2) and the mean duration of diabetes was 8 +/- 6 years. Both the diet and diet plus exercise groups showed significant body weight loss compared with the control group (P < 0.05). However, the visceral fat area was reduced only in the diet and exercise group (P = 0.017) and the subcutaneous fat area was reduced only in the diet group (P = 0.009). Mean energy intake was an independent determinant of the change in subcutaneous fat area (P = 0.020) and mean total anergy expenditure was an independent determinant of visceral fat area (P = 0.002). Insulin sensitivity K(ITT) was associated with physical activity energy expenditure (P = 0.006), energy intake (P = 0.047) and the change in fructosamine level (P = 0.016) but not with changes in body weight, subcutaneous fat area, visceral fat area or adipokine level. CONCLUSIONS: Exercise had an additive effect to dietary restriction on visceral fat reduction. Visceral fat area was associated with total energy expenditure, but insulin sensitivity was associated with physical activity energy expenditure.
机译:目的:我们研究了有或没有饮食限制三个月的体育锻炼对局部脂肪和胰岛素敏感性的影响,并比较了所有体育锻炼水平的总能量消耗与中度至剧烈的体育锻炼能量消耗的影响在患有2型糖尿病的肥胖女性中进行锻炼。方法:在这项随机对照试验中,我们评估了体重,腹部内脏脂肪面积,皮下脂肪面积和胰岛素敏感性的变化,以K(ITT)表示,并在加速期间监测了总能量消耗和体育锻炼能量消耗。在四个组中进行为期12周的干预:对照组,饮食,运动和饮食加运动。结果:平均体重指数为28.0 +/- 2.7 kg / m(2),糖尿病的平均病程为8 +/- 6年。饮食和饮食加运动组与对照组相比均显示出显着的体重减轻(P <0.05)。但是,仅饮食和运动组的内脏脂肪量减少(P = 0.017),仅饮食组的皮下脂肪量减少(P = 0.009)。平均能量摄入量是皮下脂肪面积变化的独立决定因素(P = 0.020),平均总无能消耗是内脏脂肪面积的独立决定因素(P = 0.002)。胰岛素敏感性K(ITT)与体育锻炼的能量消耗(P = 0.006),能量摄入(P = 0.047)和果糖胺水平的变化(P = 0.016)相关,但与体重,皮下脂肪面积,内脏的变化无关脂肪区或脂肪因子水平。结论:运动对限制内脏脂肪减少饮食有累加作用。内脏脂肪面积与总能量消耗相关,但胰岛素敏感性与体力活动能量消耗相关。

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