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首页> 外文期刊>Developmental neurorehabilitation >Effects associated with on- and off-label stimulant treatment of core autism and ADHD symptoms exhibited by children with autism spectrum disorder
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Effects associated with on- and off-label stimulant treatment of core autism and ADHD symptoms exhibited by children with autism spectrum disorder

机译：对自闭症谱系障碍儿童表现出的核心自闭症和ADHD症状进行标签上和标签外兴奋剂治疗相关的效果

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Objective: Families of children with autism spectrum disorder are barraged by different treatment options. Some of these options have the support of empirical evidence while others do not. Stimulant treatments are typically utilized to treat symptoms of ADHD indicating an on-label use of such treatment. Methods: This study examines the association of stimulant treatment with the on- (symptoms of ADHD) and off- (symptoms of ASD) label symptoms among children with ASD via a non-clinical, population-based sample. Results: Results indicate no significant association of stimulant treatment with a reduction of on- or off-label symptoms among children with ASD. Conclusion: Stimulant medications utilized in the treatment of DSM core symptoms of autism spectrum disorder would be considered an off-label use because there is limited evidence to support that stimulants are effective in treating core symptoms of ASD, which is supported by the results of the current study.
机译：目的：自闭症谱系障碍儿童的家庭受到不同治疗方案的困扰。其中一些选择有经验证据的支持，而另一些则没有。刺激性治疗通常用于治疗多动症的症状，表明该治疗在标签上的使用。方法：本研究通过非临床的，基于人群的样本，研究了兴奋剂治疗与ASD儿童的on（ADHD症状）和off（ASD症状）症状之间的关系。结果：结果表明，在ASD儿童中，兴奋剂治疗与减少标签上或标签外症状无明显关联。结论：用于治疗自闭症谱系障碍的DSM核心症状的兴奋剂药物应被视为标签外使用，因为仅有有限的证据支持兴奋剂可有效治疗ASD的核心症状，这一点得到了结果的支持。目前的研究。

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