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Giant cell-rich osteosarcoma of the parotid gland: An exceptionally rare entity at an unusual site

机译:腮腺巨大的富含细胞的骨肉瘤:在异常部位异常罕见的实体

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摘要

Giant cell-rich osteosarcoma is a rare histologic variant of conventional osteosarcoma that affects mainly the extremities. Extraskeletal giant cell-rich osteosarcoma is therefore exceedingly rare. Here, we report the first case of this uncommon tumor involving the parotid gland in a 62-year-old male who presented with initial right jaw swelling. Radiologic work-up revealed a 6.2 cm mass involving the right parotid gland. Fine-needle aspiration cytology showed numerous multinucleated giant cells in a background of dyshesive epithelioid cells and rare clusters of spindle stromal cells, suspicious for malignancy. The subsequent excisional biopsy showed histopathologic features diagnostic for giant cell-rich osteosarcoma. Diagn. Cytopathol. 2016;44:1107-1111. (c) 2016 Wiley Periodicals, Inc.
机译:富含细胞的巨型骨肉瘤是常规骨肉瘤的一种罕见的组织学变异,主要影响四肢。因此,骨骼外巨细胞丰富的骨肉瘤极为罕见。在这里,我们报告了这种不常见的肿瘤,其中第一例是腮腺的一名62岁男性患者,该男性患者最初出现了右下颌肿胀。放射学检查发现肿块累及右侧腮腺6.2厘米。细针穿刺细胞学检查显示,背景为上皮样上皮细胞和稀疏的纺锤体基质细胞簇,形成多核巨细胞,可疑恶变。随后的切除活检显示诊断出富含细胞的巨大骨肉瘤的组织病理学特征。诊断细胞病。 2016; 44:1107-1111。 (c)2016年威利期刊有限公司

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