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首页> 外文期刊>Digestive Diseases and Sciences >Durability of Hepatitis B e Antigen Seroconversion in Chronic Hepatitis B Patients Treated with Entecavir or Tenofovir
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Durability of Hepatitis B e Antigen Seroconversion in Chronic Hepatitis B Patients Treated with Entecavir or Tenofovir

机译:恩替卡韦或替诺福韦治疗的慢性乙型肝炎患者乙型肝炎抗原血清转换的持久性

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摘要

Loss of HBeAg and development of anti-HBe (seroconversion) is seen as a milestone and endpoint in the treatment of HBeAg-positive patients with chronic hepatitis B (CHB). Among patients treated with nucleos(t)ide analogs (NA), recurrent viremia is common after discontinuation of therapy. Entecavir (ETV) and tenofovir (TDF) are highly potent NA. The durability of virological response and HBeAg seroconversion in patients treated with these agents is not well studied.
机译:HBeAg的丧失和抗HBe的发展(血清转化)被视为治疗慢性乙型肝炎(CHB)的HBeAg阳性患者的一个里程碑和终点。在接受核苷酸(t)ide类似物(NA)治疗的患者中,停药后复发病毒血症很常见。恩替卡韦(ETV)和替诺福韦(TDF)是非常有效的NA。用这些药物治疗的患者的病毒学应答和HBeAg血清转化的持久性尚未得到很好的研究。

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