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首页> 外文期刊>Drug discovery today >Drug resistance: a growing problem.
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Drug resistance: a growing problem.

机译：耐药性：一个日益严重的问题。

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These are nice dreams, but the reality is that drug resistance is a huge problem. The Holy Grail of antibiotic research is to discover the drug target and associated drug scaffold that are not prone to drug resistance. Alas, this Holy Grail has not yet been found, and fewer people are now looking.Drug resistance is defined as the reduction in effectiveness of a drug to cure a disease or improve patient symptoms. Commonly, the term is used in the context of diseases caused by pathogens, for example, bacteria, fungi, parasites and viruses, where it is an enormous challenge. However, as we will see, drug resistance is not restricted to infectious disease, and has emerged in other disease states as well.
机译：这些都是美梦，但现实是耐药性是一个巨大的问题。抗生素研究的圣杯是发现不易产生耐药性的药物靶标和相关的药物支架。 las，尚未找到这种圣杯，现在正在寻找的人越来越少。耐药性定义为药物治疗疾病或改善患者症状的有效性下降。通常，该术语用于由病原体引起的疾病，例如细菌，真菌，寄生虫和病毒，这是一个巨大的挑战。但是，正如我们将看到的，耐药性不仅限于传染病，而且在其他疾病状态中也已经出现。

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