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首页> 外文期刊>DMW: Deutsche Medizinische Wochenschrift >Acute coronary syndrome as a first manifestation of Churg-Strauss syndrome [Akutes Koronarsyndrom als klinische Erstmanifestation einer Churg-Strauss-Vaskulitis]
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Acute coronary syndrome as a first manifestation of Churg-Strauss syndrome [Akutes Koronarsyndrom als klinische Erstmanifestation einer Churg-Strauss-Vaskulitis]

机译：急性冠状动脉综合征是Churg-Strauss综合征的首发表现

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History and admission findings: A 53-year-old woman was admitted to our chest pain unit because of an acute coronary syndrome (non ST-elevation myocardial infarction). She complained of asthma, chronic sinusitis and involuntary weight loss, occasional fever and night sweats over the past six months. Investigations: Coronary angiography did not show any signs of macroscopic coronary artery disease, while echocardiography demonstrated a hemodynamically not significant pericardial effusion. Magnetic resonance imaging of the heart revealed a subendocardial scar, extension and localization pointing to a vascular genesis. Thoracic computed tomography revealed pulmonary opacities and blood tests showed an eosinophilia, leading to the clinical diagnosis of Churg-Strauss syndome. Treatment and course: The patient responded quickly to oral steroids, and blood parameters returned to normal. Conclusion: Acute coronary syndrome in youngish patients without classical cardiovascular risk factors is suggestive for myocarditis but also for vasculitis. Churg-Strauss syndrome usually responds quickly to immunosuppressive therapy, associated with a rather good prognosis without high mortality.
机译：病史和入院发现：一名53岁的妇女因急性冠状动脉综合征（非ST抬高型心肌梗死）而入院胸痛病房。她抱怨在过去的六个月中出现了哮喘，慢性鼻窦炎和不自主的体重减轻，偶发烧和盗汗。研究：冠状动脉造影未显示任何宏观冠状动脉疾病的迹象，而超声心动图显示血流动力学上无明显心包积液。心脏的磁共振成像显示出心内膜下的瘢痕，延伸和局部化，这表明血管发生。胸部计算机断层扫描显示肺部混浊，血液检查显示嗜酸性粒细胞增多，从而导致了Churg-Strauss综合征的临床诊断。治疗和疗程：病人对口服类固醇反应迅速，血液参数恢复正常。结论：没有经典心血管危险因素的年轻患者的急性冠状动脉综合征既可提示心肌炎，也可提示血管炎。 Churg-Strauss综合征通常对免疫抑制疗法反应迅速，预后良好，无高死亡率。

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