• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Drug and alcohol review >Abstinence-orientated buprenorphine replacement therapy for young adults in out-patient counselling.
【24h】

Abstinence-orientated buprenorphine replacement therapy for young adults in out-patient counselling.

机译：在年轻人门诊咨询中以节欲为导向的丁丙诺啡替代疗法。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

This study assessed treatment retention, compliance and completion of a 9-month buprenorphine replacement programme. In addition, changes in drug use and other relevant variables, as well as predictors of completion, were examined. Seventy-five opioid-dependent out-patients (mean age 26 years; 33% females) who aimed for opioid abstinence were enrolled into the study. Assessments were undertaken prior to buprenorphine induction and again at 3, 6 and 9 months. Forty patients (53%) completed the buprenorphine programme. At 9 months, 67 patients (87%) were still in counselling. Mean attendance rates for buprenorphine dosing and counselling sessions were 0.91 and 0.74, respectively. There were significant and persistent reductions in drug use during treatment with, however, a reversed tendency in the 9th month. Psychiatric problems escalated at 9 months, and three patients died during the detoxification phase. Completion was predicted by fewer previous treatment episodes. Detoxification from buprenorphine is associated with substantial psychological distress and an increased death risk. Buprenorphine replacement therapy should be continued until the patient chooses to leave, and close monitoring during the detoxification phase is essential.
机译：这项研究评估了9个月丁丙诺啡替代计划的治疗保留率，依从性和完成情况。此外，还检查了药物使用和其他相关变量的变化以及完成情况的预测因素。旨在戒断阿片类药物的75名阿片类依赖门诊患者（平均年龄26岁;女性占33％）被纳入研究。在丁丙诺啡诱导之前以及在3、6和9个月时进行评估。 40名患者（53％）完成了丁丙诺啡方案。在9个月时，仍有67例患者（占87％）正在接受咨询。丁丙诺啡剂量和咨询时间的平均出勤率分别为0.91和0.74。治疗期间药物的使用量持续大量减少，但在第9个月出现了逆转趋势。精神病问题在9个月后升级，三名患者在排毒阶段死亡。通过较少的先前治疗发作来预测完成。丁丙诺啡的解毒与严重的心理困扰和死亡风险增加有关。丁丙诺啡替代治疗应继续进行，直到患者选择离开为止，并且在排毒阶段进行密切监测至关重要。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号