A FACILE SYNTHESIS OF 1,2-DIHYDROISOQUINOLINES BY THREE-COMPONENT REACTION

Kentaro Iso; Salprima Yudha S; Menggenbateer

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A FACILE SYNTHESIS OF 1,2-DIHYDROISOQUINOLINES BY THREE-COMPONENT REACTION

机译：三元反应轻松合成1,2-二氢异喹啉

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摘要

1,2-Dihydroisoquinoline frameworks are constructed efficiently by three-component reactions with ortho-alkynylbenzaldehydes,primary amines,and pronucleophiles under mild conditions.Isoquinoline and its derivatives constitute an important class of heterocyclic compounds that are of pharmacological significance and represent useful building blocks for natural products synthesis.

机译：1,2-二氢异喹啉骨架可通过在温和条件下与邻炔基苯甲醛，伯胺和亲核试剂进行三组分反应而高效构建。异喹啉及其衍生物构成一类重要的杂环化合物，具有重要的药理学意义并代表着有用的结构单元天然产物合成。

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《Heterocycles: An International Journal for Reviews and Communications in Heterocyclic Chemistry》 |2007年第0期|共12页
作者
Kentaro Iso; Salprima Yudha S; Menggenbateer;
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正文语种 eng
中图分类杂环化合物;
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1. A FACILE SYNTHESIS OF 1,2-DIHYDROISOQUINOLINES BY THREE-COMPONENT REACTION [J] . Kentaro Iso, Salprima Yudha S, Menggenbateer Heterocycles: An International Journal for Reviews and Communications in Heterocyclic Chemistry . 2007,第0期

机译：三元反应轻松合成1,2-二氢异喹啉
2. Synthesis of 1-(1H-Indol-3-yl)-1,2-dihydroisoquinolines via AgOTf-Catalyzed Three-Component Reactions of 2-Alkynylbenzaldehydes, Amines, and Indoles [J] . Xingxin Yu, Jie Wu Journal of combinatorial chemistry . 2010,第2期

机译：通过AgOTf催化的2-炔基苯甲醛，胺和吲哚的三组分反应合成1-（1H-Indol-3-yl）-1,2-二氢异喹啉
3. Rh-2(OAc)(4)-AgOTf Cooperative Catalysis in Cyclization/Three-Component Reactions for Concise Synthesis of 1,2-Dihydroisoquinolines [J] . Guo ZQ, Cai M, Jiang J, Organic letters . 2010,第4期

机译：Rh-2（OAc）（4）-AgOTf协同催化环化/三组分反应，合成1,2-二氢异喹啉
4. Palladium-Catalyzed Cycloaddition of Chloroform to o-Alkynylaryl Aldimines: Synthesis of 1-Trichloro-1,2-dihydroisoquinolines [C] . Hiroyuki Saito, Hiroyuki Nakamura Symposium on Organometallic Chemistry . 2007

机译：钯催化的氯仿环加成氯仿至O-炔基族醛喹啉：1-三氯-1,2-二羟基喹啉的合成
5. Synthesis of (1R,2R)-N1,N2-Dibenzylcyclohexane-1,2-diamine as an Auxiliary for a Stereoselective 1,4 Conjugate Addition Reaction; Construction of Polymer Bound (1R,2R)- 1,2-Cyclohexanediamine to evaluate the Solid-Phase Counterpart, and Methodology Development for Synthesis of Functionalized Oligothiophenes. [D] . Poorjahanshah, Homer. 2016

机译：（1R，2R）-N1，N2-二苄基环己烷-1，2-二胺作为立体选择性1，4共轭加成反应的助剂的合成；聚合物结合的（1R，2R）-1,2-环己二胺的构建以评价固相配对物，以及功能化寡聚噻吩的合成方法开发。
6. Development of Novel and Efficient Processes for the Synthesis of 5-Amino and 5-Iminoimidazo[1,2-a]imidazoles via Three-Component Reaction Catalyzed by Zirconium(IV) Chloride [O] . Mohsine Driowya, Régis Guillot, Pascal Bonnet, 1970

机译：氯化锆（IV）催化三组分反应合成5-氨基和5-氨基咪唑并[1,2-a]咪唑的新颖高效方法的进展
7. A Simple and Efficient Synthesis of Highly Substituted Indeno1,2-bpyrrole and Acenaphtho1,2-bpyrrole Derivatives by Tandem Three-Component Reactions [O] . Xiaodong Tang, Songlei Zhu, Ying Ma, 2018

机译：通过串联三分反应简单有效地合成高级取代的Indeno 1,2-B吡咯和AceNaphtho 1,2-B吡咯衍生物

A FACILE SYNTHESIS OF 1,2-DIHYDROISOQUINOLINES BY THREE-COMPONENT REACTION

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