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首页> 外文期刊>Japanese Journal of Ophthalmology >Influence of macular microcirculation and retinal thickness on visual acuity in patients with branch retinal vein occlusion and macular edema.
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Influence of macular microcirculation and retinal thickness on visual acuity in patients with branch retinal vein occlusion and macular edema.

机译：黄斑微循环和视网膜厚度对视网膜分支静脉阻塞和黄斑水肿患者视力的影响。

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摘要

PURPOSE: To investigate perifoveal capillary blood flow velocity and retinal thickness at the central fovea in patients with branch retinal vein occlusion (BRVO) and macular edema and to assess their relation with visual acuity and visual prognosis. METHODS: Eighteen patients with BRVO and 16 healthy volunteers were compared. Perifoveal capillary blood flow velocity was measured on fluorescein angiograms with a scanning laser ophthalmoscope by the tracing method. Retinal thickness was measured at the central fovea by optical coherence tomography. Best-corrected visual acuity (BCVA) was determined. RESULTS: BCVA differed significantly between patients and controls (P < 0.0001). Among patients, BCVA was negatively correlated with perifoveal capillary blood flow velocity by univariate analysis (r = -0.7916, P < 0.0001), and positively correlated with retinal thickness at the central fovea (r = 0.8970, P < 0.0001). Multivariate analysis showed that retinal thickness at the central fovea was the only independent determinant of BCVA (P < 0.0001). CONCLUSIONS: In patients with BRVO, BCVA was more strongly influenced by retinal thickness at the central fovea than by perifoveal capillary blood flow velocity.
机译：目的：探讨视网膜分支静脉阻塞（BRVO）和黄斑水肿患者的中央凹中央凹毛细血管流速和视网膜厚度，并评估其与视力和视觉预后的关系。方法：比较18例BRVO患者和16例健康志愿者。用示踪法用扫描激光检眼镜在荧光素血管造影照片上测量了小叶周围毛细血管的血流速度。通过光学相干断层扫描在中央凹中央测量视网膜厚度。确定最佳矫正视力（BCVA）。结果：患者和对照组之间的BCVA存在显着差异（P <0.0001）。在患者中，BCVA通过单因素分析与小凹周围毛细血管流速呈负相关（r = -0.7916，P <0.0001），而与中央凹中央的视网膜厚度呈正相关（r = 0.8970，P <0.0001）。多变量分析表明，中央凹中央的视网膜厚度是BCVA的唯一独立决定因素（P <0.0001）。结论：在BRVO患者中，中央凹处视网膜厚度的影响远大于中央凹周围毛细血管流速对BCVA的影响。

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