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首页> 外文期刊>Circulation journal >Relation between white blood cell counts and myocardial reperfusion in patients with recanalized anterior acute myocardial infarction.
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Relation between white blood cell counts and myocardial reperfusion in patients with recanalized anterior acute myocardial infarction.

机译：肾小管再狭窄前路急性心肌梗死患者白细胞计数与心肌再灌注的关系。

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摘要

Background The clinical significance of the white blood cell (WBC) count on admission in relation to the duration of ischemia in acute myocardial infarction (AMI) remains unclear. Methods and Results The relationship of the WBC count on admission to myocardial reperfusion was examined in 135 patients with recanalization of an anterior AMI within 6 h of symptom onset. Patients were classified according to the WBC count on admission: Group L (n=75), WBC count <12,000 cells/mm(3) and group H (n=60), WBC count >/=12,000 cells/mm(3). Peak creatine kinase (CK) was higher and impaired myocardial reperfusion, defined as a myocardial blush grade of 0/1, was more frequent in group H than in group L. Among the patients in group H, those with early (3 h) recanalization; however, peak CK and the incidence of impaired myocardial reperfusion were similar in these subgroups of patients. Multivariate analysis showed that WBC count>/=12,000 cells/mm(3) on admission was an independent predictor of impaired myocardial reperfusion in patients with early recanalization (odds ratio 7.9, p=0.04), but not in those with late recanalization. Conclusions A higher WBC count may be associated with progression of myocardial damage after recanalization in patients with early recanalization of an anterior AMI.
机译：背景技术急性心肌梗死（AMI）的缺血持续时间与入院时白细胞（WBC）计数的临床意义尚不清楚。方法和结果检查了135例症状发作后6小时内AMI再通的患者中WBC计数与入院与心肌再灌注的关系。根据入院时WBC计数对患者进行分类：L组（n = 75），WBC计数<12,000细胞/ mm（3）和H组（n = 60），WBC计数> / = 12,000细胞/ mm（3） 。 H组的峰值肌酸激酶（CK）较高，并且心肌再灌注受损（定义为心肌腮红等级为0/1）在H组比L组更频繁。H组患者中，早期（ 3 h）再通的QRS评分;然而，在这些亚组患者中，CK峰值和心肌再灌注受损的发生率相似。多因素分析显示，入院时白细胞计数> / = 12,000细胞/ mm（3）是早期再通患者（赔率比7.9，p = 0.04）受损的心肌再灌注的独立预测因子，而晚期再通患者则无此效应。结论AMI前部再通的患者，WBC计数升高可能与再通后心肌损害的进展有关。

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