...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Circulation journal >Primary percutaneous coronary intervention lowers the incidence of ischemic mitral regurgitation in patients with acute ST-elevated myocardial infarction.
【24h】

Primary percutaneous coronary intervention lowers the incidence of ischemic mitral regurgitation in patients with acute ST-elevated myocardial infarction.

机译：原发性经皮冠状动脉介入治疗可降低急性ST抬高型心肌梗死患者缺血性二尖瓣关闭不全的发生率。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

BACKGROUND: The impact of primary percutaneous coronary intervention (PCI) for acute ST-elevated myocardial infarction (STEMI) on the incidence of ischemic mitral regurgitation (IMR) is unclear. METHODS AND RESULTS: Between January 2000 and December 2004, 318 patients presenting with first acute STEMI were enrolled in this study. Two hundred and twelve (66.67%) patients received PCI (PCI group), and 106 age- and Killip class-matched patients received medical management (non-PCI group). The median duration of follow up was 40.46 months. Compared to the non-PCI group, the PCI group had 14.6% (9.9% vs 24.5%) fewer patients with moderate or severe IMR (P<0.001). Univariate analysis demonstrated IMR was significantly associated with advanced age, higher Killip score, and posterior myocardial infarction (MI). Moreover, IMR was strongly associated with a lower left ventricular (LV) ejection fraction, larger left atrial dimension (LAd), and a larger LV end-systolic and LV end-diastolic volumes (LVEDV) (all P<0.01). Multivariate analysis revealed the odds of IMR in the PCI group was 0.208 times those of the non-PCI group (P<0.001). Additionally, moderate or severe IMR was independently correlated with advanced age, inferior MI, Killip class >/=3, larger LAd, and larger LVEDV (all P<0.05). Furthermore, long-term survival time was longer in the PCI group without IMR than in the non-PCI group with IMR (all P<0.01). CONCLUSIONS: PCI for first acute STEMI was associated with lower incidence of IMR. Advanced age, inferior MI, Killip class >/=3, larger LAd and LVEDV were risk factors associated with IMR development.
机译：背景：急性ST抬高型心肌梗死（STEMI）的主要经皮冠状动脉介入治疗（PCI）对缺血性二尖瓣关闭不全（IMR）发生率的影响尚不清楚。方法与结果：2000年1月至2004年12月，本研究共纳入318例首发急性STEMI患者。一百二十二例（66.67％）患者接受了PCI（PCI组），而106例年龄和基利分类匹配的患者接受了医疗管理（非PCI组）。中位随访时间为40.46个月。与非PCI组相比，PCI组中度或重度IMR患者减少了14.6％（9.9％比24.5％）（P <0.001）。单因素分析表明，IMR与高龄，较高的Killip评分和后心肌梗死（MI）密切相关。此外，IMR与较低的左心室（LV）射血分数，较大的左心房尺寸（LAd）和较大的LV收缩末期容积和LV舒张末期容积（LVEDV）密切相关（所有P <0.01）。多因素分析显示，PCI组IMR的几率是非PCI组的0.208倍（P <0.001）。此外，中度或重度IMR与年龄，MI下级，Killip分类> / = 3，较大LAd和较大LVEDV独立相关（所有P <0.05）。此外，没有IMR的PCI组的长期生存时间比有IMR的非PCI组长（所有P <0.01）。结论：首次急性STEMI的PCI与IMR的发生率较低有关。高龄，MI下级，Killip等级> / = 3，较大的LAd和LVEDV是与IMR发生相关的危险因素。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号