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首页> 外文期刊>Circulation journal >Effect of Cibenzoline and Atenolol Administration on Dynamic Left Ventricular Obstruction Due to Sigmoid-Shaped Septum
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Effect of Cibenzoline and Atenolol Administration on Dynamic Left Ventricular Obstruction Due to Sigmoid-Shaped Septum

机译：乙苯胆碱和阿替洛尔给药对乙状结肠间隔动性左室梗阻的影响

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摘要

Obstruction of the left ventricular outflow tract (LVOT) is usually complicated by hypertrophic cardiomyopathy or left ventricular hypertrophy. It occurs rarely in cases of sigmoid-shaped septum (SS), which are considered as a normal part of the aging process. The 2 cases of SS with obstruction of the LVOT were observed. Their complaints were dyspnea on effort and exercise increased the left ventricular pressure gradient. In both cases, atenolol administration decreased rest pressure gradient. Moreover, additional cibenzoline administration decreased the pressure gradient caused by exercise. It is emphasized that dual therapy with cibenzoline and atenolol is effective in resolving the obstruction of the LVOT caused by SS.
机译：肥厚型心肌病或左心室肥大通常会并发左室流出道（LVOT）阻塞。在乙状结肠（SS）的情况下很少发生这种情况，后者被认为是衰老过程的正常部分。观察到2例SS伴有LVOT阻塞。他们的主诉是呼吸困难和运动增加了左心室压力梯度。在两种情况下，阿替洛尔的给药均降低了静息压力梯度。此外，额外的环苯苄胺给药可降低运动引起的压力梯度。要强调的是，用cibenzoline和阿替洛尔的双重疗法可有效解决SS引起的LVOT阻塞。

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