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High incidence of chromosomal abnormalities in large-headed and multiple-tailed spermatozoa.

机译:大头和多尾精子中染色体异常的发生率很高。

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To date, several studies of aneuploidy rate in spermatozoa from infertile men have been published. Most of them found an increase incidence of aneuploid spermatozoa in infertile patients compared with normal donors (Moosani et al, 1995; Finkelstein et al, 1998; McInnes et al, 1998; Pang et al, 1999; Rives et al, 1999; Vegetti et al, 2000). However, in other studies, no differences in aneuploidy rates between fertile and infertile men were reported (Miharuet al, 1994; Guttenbach et al, 1997). The evaluated patients often showed different types of sperm parameter impairments, including oligo-, astheno-, oligoastheno-, oligoterato-, oligoastenoterato-, asthenoteratozoospermia, and unexplained infertility, and this may be responsible, at least in part, for the discrepancies observed in the results.
机译:迄今为止,已经发表了一些关于不育男性精子中非整倍体率的研究。他们中的大多数人发现与正常供体相比,不育患者中非整倍体精子的发生率增加(Moosani等,1995; Finkelstein等,1998; McInnes等,1998; Pang等,1999; Rives等,1999; Vegetti等等,2000)。但是,在其他研究中,没有报道可育和不育男性之间非整倍体率的差异(Miharuet等,1994; Guttenbach等,1997)。被评估的患者经常表现出不同类型的精子参数损伤,包括少精,无神精,少精,无精,少精,不精,无精子症和不明原因的不孕,这可能至少部分是造成观察到的差异的原因。结果。

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