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首页> 外文期刊>Journal of Agricultural and Food Chemistry >Fresh israeli jaffa sweetie juice consumption improves lipid metabolism and increases antioxidant capacity in hypercholesterolemic patients suffering from coronary artery disease: studies in vitro and in humans and positive changes in albumin and fib
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Fresh israeli jaffa sweetie juice consumption improves lipid metabolism and increases antioxidant capacity in hypercholesterolemic patients suffering from coronary artery disease: studies in vitro and in humans and positive changes in albumin and fib

机译：食用新鲜的以色列jaffa甜心果汁可改善患有冠心病的高胆固醇血症患者的脂质代谢并提高其抗氧化能力：体外和人体研究以及白蛋白和fib的阳性变化

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The contents of the bioactive compounds in the pummelo-grapefruit hybrid juice named Israeli Jaffa Sweetie and their influence on humans suffering from hypercholesterolemia were studied. It was found that Sweetie juice has a high content of bioactive compounds and a high antioxidant potential. Then 72 hypercholesterolemic patients, ages 43-71 years, after coronary bypass surgery recruited from the Institute pool of volunteers, were randomly divided into two experimental (EG1 and EG2) groups and one control (CG) group, each comprising 24 patients. The diets of EG1 and EG2 patients were daily supplemented with 100 or 200 mL of fresh Sweetie juice, respectively. Before and after diet consumption serum lipid levels, albumin and fibrinogen fractions, and their antioxidant capacities were determined. After 30 consecutive days of Sweetie juice supplemented diets, improvements in serum lipids levels were found in EG1 and EG2 versus CG: (a) total cholesterol, 7.34 versus 8.02 mmol/L, -9.5%, and 6.73 versus 8.02mmol/L, -16.1%, respectively; (b) low-density lipoprotein cholesterol, 5.63 versus 6.37 mmol/L, -11.6%, and 5.03 versus 6.37 mmol/L, -21.0%, respectively; (c) total glycerides, 2.01 versus 2.27 mmol/L, -11.5%, and 1.71 versus 2.27 mmol/L, -24.7%, respectively. Serum albumin concentration was increased but not significantly in EG1 and EG2 versus CG: 47.5 versus 44.5 g/L, +6.7%, and 47.9 versus 44.5 g/L, +7.6%, respectively. A significant increase in the serum, albumin, and fibrinogen antioxidant capacities in EG2 and to a lesser degree in EG1 was observed. No changes in the CG were found. In conclusion, fresh Sweetie juice contains high quantities of bioactive compounds and has a high antioxidant potential. Diet supplemented with this juice positively influences serum lipid, albumin, and fibrinogen levels and their antioxidant capacities. Addition of fresh Sweetie juice to generally accepted diets may be beneficial for hypercholesterolemic patients.
机译：研究了柚子-葡萄柚混合汁中的生物活性化合物的含量，即以色列Jaffa Sweetie及其对高胆固醇血症人类的影响。发现甜心汁具有高含量的生物活性化合物和高抗氧化潜能。然后从研究所的志愿者库中招募的72例年龄在43-71岁的高胆固醇血症患者被随机分为两个实验组（EG1和EG2）和一个对照组（CG），每组包括24名患者。每天分别向EG1和EG2患者的饮食中补充100或200 mL新鲜的甜心果汁。饮食饮食前后测定血清脂质水平，白蛋白和纤维蛋白原部分及其抗氧化能力。在连续30天补充甜心果汁饮食后，发现EG1和EG2与CG相比血脂水平有所改善：（a）总胆固醇，7.34与8.02 mmol / L，-9.5％和6.73与8.02mmol / L，-分别为16.1％; （b）低密度脂蛋白胆固醇分别为5.63对6.37 mmol / L，-11.6％和5.03对6.37 mmol / L，-21.0％; （c）总甘油酯分别为2.01对2.27 mmol / L，-11.5％和1.71对2.27 mmol / L，-24.7％。与CG相比，EG1和EG2的血清白蛋白浓度增加但不明显：分别为47.5和44.5 g / L，增加6.7％，以及47.9和44.5 g / L，增加7.6％。观察到在EG2中血清，白蛋白和纤维蛋白原抗氧化剂的能力显着增加，而在EG1中则降低了。 CG没有变化。总之，新鲜的甜心果汁含有大量的生物活性化合物，并具有很高的抗氧化潜力。补充了这种果汁的饮食会积极影响血清脂质，白蛋白和纤维蛋白原水平及其抗氧化能力。在普遍接受的饮食中添加新鲜的甜蜜果汁可能对高胆固醇血症患者有益。

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