OVINE METABOLISM OF ZEARALENONE TO ALPHA-ZEARALANOL (ZERANOL)

Miles CO; Erasmuson AF; Wilkins AL; Towers NR; Smith BL; Garthwaite

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OVINE METABOLISM OF ZEARALENONE TO ALPHA-ZEARALANOL (ZERANOL)

机译：玉米赤霉烯酮对α-玉米醇的代谢

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This is the first report of a metabolic conversion in animals of zearalenone to zearalanols. Zearalenone was labeled with deuterium by base-catalyzed isotope exchange. The labeled zearalenone, in the form of its beta-cyclodextrin inclusion complex, was administered orally and intravenously to sheep. In addition to deuteriozearalenone glucuronide, analysis of the urine revealed the presence of deuteriated alpha- and beta-zearalenol and alpha- and beta-zearalanol glucuronides. No zearalanone was detected in the urine. The problem of cis-trans isomerization of zearalenone in the presence of sunlight is also discussed.

机译：这是玉米赤霉烯酮代谢为泽拉诺醇的动物的代谢转化的首次报道。玉米赤霉烯酮通过碱催化的同位素交换被氘标记。将标记的玉米赤霉烯酮以其β-环糊精包合物的形式口服和静脉内给予绵羊。除了氘化玉米赤霉烯酮葡糖醛酸外，对尿液的分析还显示了氘化的α-和β-玉米赤霉烯醇以及α-和β-玉米醇的葡糖醛酸。尿液中未检出泽拉酮。还讨论了在阳光存在下玉米赤霉烯酮的顺反异构化问题。

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来源
《Journal of Agricultural and Food Chemistry》 |1996年第10期|共7页
作者
Miles CO; Erasmuson AF; Wilkins AL; Towers NR; Smith BL; Garthwaite;
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正文语种 eng
中图分类农业化学;营养卫生、食品卫生;农业科学;
关键词
Zeranol; Zearalanol; Zearalenone; Zearalenol; Metabolism; Residue; Fusarium graminearum; Derivatives; Mycotoxins; Pasture;

机译：玉米醇;泽拉洛醇;泽拉烯酮;泽拉烯醇;代谢;残基;禾本科镰刀菌;衍生物;霉菌毒素;牧草;

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专利

1. OVINE METABOLISM OF ZEARALENONE TO ALPHA-ZEARALANOL (ZERANOL) [J] . Miles CO, Erasmuson AF, Wilkins AL, Journal of Agricultural and Food Chemistry . 1996,第10期

机译：玉米赤霉烯酮对α-玉米醇的代谢
2. Interactions of zearalanone, alpha-zearalanol, beta-zearalanol, zearalenone-14-sulfate, and zearalenone-14-glucoside with serum albumin [J] . Faisal Zelma, Voros Virag, Fliszar-Nyul Eszter, Mycotoxin Research . 2020,第4期

机译：Zearalanone，α-Zealalanol，β-氧化醇，Zearalenone-14-硫酸盐和Zearalenone-14-葡萄糖苷与血清白蛋白相互作用
3. Determination of the cross-reactivities for alpha-zearalenol, beta-zearalenol, zearalanone, alpha-zearalanol, and beta-zearalanol on three commercial immunoaffinity columns targeting zearalenone [J] . Erbs M, Hartmann N, Bucheli TD Journal of AOAC International . 2007,第4期

机译：在靶向Zealalenone的三个商业免疫亲和柱上测定α-Zearalenol，β-酸甲酚，Zealalanone，α-羟烷醇和β-羟烷醇的交叉反应性
4. The effect of condensed tannins in sulla (Hedysarum coronarium) on 4-methylphenol metabolism in the ovine gastrointestinal tract during late lactation [C] . N.C. ROY, K. FRASER, G.A. LANE, Conference of the New Zealand Society of Animal Production . 2005

机译：Sulla（Hebysarum coronarium）在晚期泌乳期间含苏拉（Hebyasarum冠状胰岛冠状胰岛）在4-甲基苯酚代谢中的影响
5. Effects of intermittent umbilical cord occlusions on metabolism, cardiovascular responses and brain injury in the ovine fetus. [D] . Hamrahi, Hedieh. 2008

机译：间歇性脐带闭塞对绵羊胎儿代谢，心血管反应和脑损伤的影响。
6. Metabolism of Zearalenone in the Rumen of Dairy Cows with and without Application of a Zearalenone-Degrading Enzyme [O] . Christiane Gruber-Dorninger, Johannes Faas, Barbara Doupovec, 2021

机译：乳酸奶牛瘤瘤中的Zearalenone的代谢无需施用Zearalenone降解酶
7. Electrochemical Detection of Zeranol and Zearalenone Metabolic Analogs in Meats and Grains by Screen-Plated Carbon-Plated Disposable Electrodes [O] . Chi-Chung Chou, Jen-Lin Chang, Wei-Shao She, 2013

机译：筛涂碳沉积一次性电极电化学检测肉类和谷物中的泽拉醇和玉米赤霉烯酮代谢类似物

OVINE METABOLISM OF ZEARALENONE TO ALPHA-ZEARALANOL (ZERANOL)

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