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首页> 外文期刊>Journal of Applied Polymer Science >12-Crown-4-Ether and Tri(ethylene glycol) Dimethyl-Ether Plasma-Coated Stainless Steel Surfaces and Their Ability to Reduce Bacterial Biofilm Deposition
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12-Crown-4-Ether and Tri(ethylene glycol) Dimethyl-Ether Plasma-Coated Stainless Steel Surfaces and Their Ability to Reduce Bacterial Biofilm Deposition

机译：12冠4醚和三（乙二醇）二甲醚等离子涂层不锈钢表面及其减少细菌生物膜沉积的能力

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摘要

It has been demonstrated that surfaces coated with poly(ethylene glycol) (PEG) are capable of reducing protein adsorption, bacterial attachment, and biofilm formation. In this communication cold-plasma-enhanced processes were employed for the deposition of PEG-like structures onto stainless steel surfaces. Stainless steel samples were coated under 1,4,7,10-tetraoxacyclododecane (12-crown-4)-ether and Tri(ethylene glycol) dimethyl ether (triglyme)-radio frequency (RF)-plasma conditions. The chemistry and characteristics of plasma-coated samples and biofilms were investigated using electron spectroscopy for chemical analysis (ESCA), atomic force microscopy (AFM), and water contact angle analysis. ESCA analysis indicated that the plasma modification resulted in the deposition of PEG-like structures, built up mainly of -CH_2-CH_2-O-linkages. Plasma-coated stainless steel surfaces were more hydrophilic and had lower surface roughness values compared to those of unmodified substrates. Compared to the unmodified surface. they not only significantly reduced bacterial attachment and biofilm formation in the presence of a mixed culture of Salmonella thphimurium, Staphylococcus epidermidis, and Pseudomonas fluorescens but also influenced the chemical characteristics of the biofilm. Thus, plasma deposition of PEG-like structures will be of use to the food-processing and medical industries searching for new technologies to reduce bacterial contamination.
机译：已经证明，涂有聚乙二醇（PEG）的表面能够减少蛋白质吸附，细菌附着和生物膜形成。在这种交流中，采用冷等离子体增强工艺将PEG样结构沉积到不锈钢表面上。不锈钢样品在1,4,7,10-四氧环十二烷（12-crown-4）-醚和三（乙二醇）二甲醚（三甘醇二甲醚）-射频（RF）-等离子体条件下进行涂层。使用电子光谱法对化学分析（ESCA），原子力显微镜（AFM）和水接触角分析技术研究了血浆涂层样品和生物膜的化学特性。 ESCA分析表明，等离子体修饰导致主要由-CH_2-CH_2-O-键建立的PEG样结构的沉积。与未改性的基材相比，等离子涂层的不锈钢表面更亲水，表面粗糙度较低。与未修饰的表面相比。它们不仅在沙门氏菌，表皮葡萄球菌和荧光假单胞菌的混合培养物中显着减少了细菌附着和生物膜的形成，而且还影响了生物膜的化学特性。因此，PEG样结构的等离子体沉积将用于食品加工和医疗行业，以寻找减少细菌污染的新技术。

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