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首页> 外文期刊>Journal of Biomechanics >Comparison of micro-level and continuum-level voxel models of the proximal femur.
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Comparison of micro-level and continuum-level voxel models of the proximal femur.

机译：股骨近端的微观和连续水平体素模型的比较。

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摘要

Continuum-level finite element (FE) models became standard computational tools for the evaluation of bone mechanical behavior from in vivo computed tomography scans. Such scans do not account for the anisotropy of the bone. Instead, local mechanical properties in the continuum-level FE models are assumed isotropic and are derived from bone density, using statistical relationships. Micro-FE models, on the other hand, incorporate the anisotropic structure in detail. This study aimed to quantify the effects of assumed isotropy, by comparing continuum-level voxel models of a healthy and a severely osteoporotic proximal femur with recently analyzed micro-FE models of the same bones. The micro-model element size was coarsened to generate continuum FE models with two different element sizes (0.64 and 3.04 mm) and two different density-modulus relationships found in the literature for wet and ash density. All FE models were subjected to the same boundary conditions that simulated a fall to the side, and the stress and strain distributions, model stiffness and yield load were compared. The results indicated that the stress and strain distributions could be reproduced well with the continuum models. The smallest differences between the continuum-level model and micro-level model predictions of the stiffness and yield load were obtained with the coarsest element size. Better results were obtained for both continuum-element sizes when isotropic moduli were based on ash density rather than wet density.
机译：连续体级有限元（FE）模型已成为用于从体内计算机断层扫描中评估骨骼力学行为的标准计算工具。这样的扫描不能说明骨骼的各向异性。取而代之的是，假定连续统水平有限元模型中的局部力学性能是各向同性的，并使用统计关系从骨密度中得出。另一方面，Micro-FE模型详细地包含了各向异性结构。这项研究旨在通过比较健康和严重骨质疏松性股骨的连续体水平体素模型与最近分析过的相同骨骼的micro-FE模型来量化假定的各向同性的影响。微观模型元素的大小被粗化以生成具有两种不同元素大小（0.64和3.04 mm）以及在湿湿灰分密度中发现的两种不同密度-模量关系的连续有限元模型。所有有限元模型都在相同的边界条件下模拟了跌落到一边，并比较了应力和应变分布，模型刚度和屈服载荷。结果表明，使用连续模型可以很好地再现应力和应变分布。连续性模型和微观模型对刚度和屈服载荷的预测之间的差异最小，而单元尺寸最大。当各向同性模量基于灰分密度而不是湿密度时，两种连续体尺寸均获得了较好的结果。

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