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首页> 外文期刊>Journal of biomedical materials research. Part B, Applied biomaterials. >Biocompatibility of polymethylmethacrylate resins used in dentistry.
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Biocompatibility of polymethylmethacrylate resins used in dentistry.

机译：牙科用聚甲基丙烯酸甲酯树脂的生物相容性。

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摘要

Biocompatibility or tissue compatibility describes the ability of a material to perform with an appropriate host response when applied as intended. Poly-methylmethacrylate (PMMA) based resins are most widely used resins in dentistry, especially in fabrication of dentures and orthodontic appliances. They are considered cytotoxic on account of leaching of various potential toxic substances, most common being residual monomer. Various in vitro and in vivo experiments and cell based studies conducted on acrylic based resins or their leached components have shown them to have cytotoxic effects. They can cause mucosal irritation and tissue sensitization. These studies are not only important to evaluate the long term clinical effect of these materials, but also help in further development of alternate resins. This article reviews information from scientific full articles, reviews, or abstracts published in dental literature, associated with biocompatibility of PMMA resins and it is leached out components. Published materials were searched in dental literature using general and specialist databases, like the PubMED database.
机译：生物相容性或组织相容性描述了材料按预期应用时具有适当宿主反应的能力。聚甲基丙烯酸甲酯（PMMA）基树脂是牙科领域最广泛使用的树脂，尤其是在义齿和正畸器具的制造中。由于各种潜在的有毒物质的浸出，它们被认为具有细胞毒性，最常见的是残留单体。对丙烯酸基树脂或其沥滤成分进行的各种体外和体内实验以及基于细胞的研究表明，它们具有细胞毒性作用。它们会引起粘膜刺激和组织致敏。这些研究不仅对于评估这些材料的长期临床效果非常重要，而且还有助于进一步开发替代树脂。本文评论来自牙科文献中发表的科学论文，评论或摘要中的信息，这些信息与PMMA树脂的生物相容性有关，并且它会滤出成分。使用常规数据库和专业数据库（例如PubMED数据库）在牙科文献中搜索已出版的材料。

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