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首页> 外文期刊>Journal of biomedical materials research. Part B, Applied biomaterials. >Degradation of the resin-dentin bonds after simulated and inhibited cariogenic challenge in an in situ model.
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Degradation of the resin-dentin bonds after simulated and inhibited cariogenic challenge in an in situ model.

机译：在原位模型中模拟和抑制致龋攻击后，树脂-牙本质键的降解。

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The aim of this study was to evaluate the resin-dentin bonds of two simplified etch-and-rinse adhesive after simulated cariogenic and inhibited cariogenic challenge in situ. Dental cavities (4 mm wide, 4 mm long, and 1.5 mm deep) were prepared in 60 bovine teeth with enamel margins. Restorations were bonded with either adhesive Adper Single Bond 2 (3MESPE) or Optibond Solo Plus (Kerr). Forty restorations were included in an intra-oral palatal appliance that was used for 10 adult volunteers while the remaining 20 dental blocks were not submitted to any cariogenic challenge [NC group] and tested immediately. For the simulated cariogenic challenge [C+DA], each volunteer dropped 20% sucrose solution onto all blocks four times a day during 14 days and distilled water twice a day. In the inhibited cariogenic challenge group [C + FA], the same procedure was done, but slurry of fluoride dentifrice (1.100 ppm) was applied instead of water. The restored bovine blocks were sectioned to obtain a slice for cross-sectional Vickers microhardness evaluation and resin-dentin bonded sticks (0.8 mm(2) ) for resin-dentin microtensile evaluation. Data were evaluated by two-way ANOVA and Tukey's tests (α = 0.05). Statistically lower microhardness values and degradation of the resin-dentin bonds were only found in the C + DW group for both adhesives. The in situ model seems to be a suitable short-term methodology to investigate the degradation of the resin-dentin bonds under a more realistic condition. ? 2012 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 100B: 1466-1471, 2012.
机译：这项研究的目的是评估模拟的致龋和抑制致癌作用后两种简化的蚀刻和漂洗粘合剂的树脂-牙本质键。在60具牙釉质边缘的牛牙中准备了牙洞（宽4毫米，长4毫米，深1.5毫米）。用粘合剂Adper Single Bond 2（3MESPE）或Optibond Solo Plus（Kerr）粘合修复体。口内appliance器械中包括40个修复体，可用于10名成年志愿者，而其余20个牙齿阻滞未接受任何致龋性挑战[NC组]，并立即进行了测试。对于模拟的致癌性攻击[C + DA]，每位志愿者在14天中每天四次向所有块中滴加20％蔗糖溶液，每天两次蒸馏水。在抑制龋齿的攻击组[C + FA]中，执行相同的步骤，但使用氟化物洁齿剂（1.100 ppm）的浆液代替水。恢复的牛块被切成薄片，以进行截面维氏显微硬度评估，并用树脂-牙本质粘合棒（0.8 mm（2））进行树脂-牙本质微张力评估。数据通过双向方差分析和Tukey检验（α= 0.05）进行评估。统计上较低的显微硬度值和树脂-牙本质键的降解仅在两种胶粘剂的C + DW组中发现。原位模型似乎是研究更现实条件下树脂-牙本质键降解的一种合适的短期方法。 ？ 2012 Wiley Periodicals，Inc. J Biomed Mater Res B部分：Appl Biomater 100B：1466-1471，2012。

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