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Isotherm of ligand adsorption on DNA at multiplicative noise

机译:乘性噪声下DNA上配体吸附的等温线

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Fluctuations of the number of ligands adsorbed on macromolecules are considered in the case when the number of ligands in the solution fluctuates under the action of fluctuations of the external medium (external noise). For the case of small filling, the multiplicative type of stochastic differential equation is obtained, describing the time variation of the number of ligands adsorbed on macromolecules. The isotherm of adsorption of ligands on DNA is obtained. It is shown that at small ligand concentrations, for some relations between adsorption parameters and the intensity of the external noise, no macromolecule adsorption of ligands takes place.
机译:在溶液中的配体数在外部介质的变动(外部噪声)的作用下变动的情况下,考虑吸附在大分子上的配体数的变动。对于小填充的情况,获得了乘法类型的随机微分方程,描述了吸附在大分子上的配体数量随时间的变化。获得配体在DNA上的吸附等温线。结果表明,在低配体浓度下,对于吸附参数与外部噪声强度之间的某些关系,不会发生配体的大分子吸附。

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