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Clinical correlates of frontal intermittent rhythmic delta activity in children.

机译:儿童额叶间歇性节律性活动的临床相关性。

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Frontal intermittent rhythmic delta activity is an electrographic pattern of unclear origin. Previously thought to correlate with deep midline and infratentorial pathology, rather, it appears to be associated with encephalopathy states in adults. The significance of frontal intermittent rhythmic delta activity in children has not been studied. We analyzed the electrographic characteristics and clinical associations of pediatric frontal intermittent rhythmic delta activity. This pattern was rarely detected, occurring in 20 of 1500 electroencephalographic (EEG) studies. Patients' ages ranged between 1.5 and 17 years. Most patients were awake and showed no signs of acute encephalopathy when frontal intermittent rhythmic delta activity occurred. Half of the children were cognitively impaired, and half had a history of epilepsy. Epileptiform activity was present in 55% of the EEG recordings. However, frontal intermittent rhythmic delta activity was part of the epileptiform discharge in only a minority of cases. The duration of frontal intermittent rhythmic delta activity bursts was longer in the mentally retarded group. Most patients did not have structural brain pathology. None had deep midline or infratentorial lesions. In conclusion, frontal intermittent rhythmic delta activity is rare in children, is not associated with acute encephalopathy or with deep midline or infratentorial lesions, and tends to occur during wakefulness. The electrographic characteristics of frontal intermittent rhythmic delta activity appear to differ between cognitively normal and mentally retarded children.
机译:额叶间歇性节律性活动是一种来源不明的电子照相模式。以前被认为与深层中线和下腹病变相关,相反,它似乎与成人的脑病状态有关。尚未研究儿童额叶间歇性节律性活动的重要性。我们分析了小儿额叶间歇性节律性三角洲活动的电图特征和临床关联。在1500例脑电图(EEG)研究中,有20例很少发现这种模式。患者的年龄在1.5至17岁之间。大多数患者清醒并且当额叶间歇性节律性三角洲活动发生时未显示急性脑病的迹象。一半的儿童有认知障碍,一半有癫痫病史。癫痫样活性存在于55%的EEG记录中。然而,额叶间歇性节律性活动仅在少数情况下是癫痫样放电的一部分。智障组额叶间歇性节律性三角洲活动爆发的持续时间较长。大多数患者没有结构性脑病理。没有人有中线或下腹部深部病变。总之,额叶间歇性节律性三角洲活动在儿童中很少见,与急性脑病或中深部或下腹肌损害无关,并且往往在清醒时发生。在认知正常和智力低下的儿童中,额叶间歇性节律性三角活动的电子特征似乎有所不同。

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