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Clinical and radiologic correlates of frontal intermittent rhythmic delta activity.

机译:额叶间歇性节律性三角活动的临床和影像学相关性。

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To assess the clinical and radiologic correlates of frontal intermittent rhythmic delta activity (FIRDA), the authors reviewed the hospital charts of patients whose EEGs depicted this EEG finding, and recorded their past medical and neurologic history, the reason for hospital admission, and their neurologic status both on admission and during EEG recordings. Laboratory results on admission and concomitant to the EEG recording, computed tomography, or MRI findings during hospital admission were also reviewed. Sixty-eight patients were assessed. The gender ratio was 1:1; mean age was 56 years. Chronic disease occurred in 78% of patients, including hypertension (34%), diabetes (32%), and renal failure (18%). On admission, renal failure (n = 34) and hyperglycemia (n = 22) were most prominent. The majority of patients had at least one abnormal laboratory result. Thirty-eight of 51 patients in whom the level of consciousness was stated during EEG were described as awake. More than half of 58 patients whose EEG background activity was stipulated demonstrated diffuse slowing, mostly in the theta range. MRI was abnormal in 15 of 17 patients. Intrahemispheric lesions, particularly ischemic and hemorrhagic, were most common (n = 10), followed by basal ganglia lacunae (n = 4). Computed tomography was abnormal in 29 of 44 patients. Hemispheric pathology, diffuse or localized, occurred in 22 patients. Frontal intermittent rhythmic delta activity is associated with mild to moderate encephalopathy and is detected principally in awake patients. Most patients in this series had chronic systemic illness. Old ischemic structural brain lesions may predispose some patients to develop FIRDA during acute metabolic derangement, such as uremia and hyperglycemia. Frontal intermittent rhythmic delta activity was not associated with EEG epileptiform activity. Deep midline lesions, posterior fossa tumors, and hydrocephalus were not detected in this series of patients with FIRDA.
机译:为了评估额叶间歇性节律性三角洲活动(FIRDA)的临床和影像学相关性,作者回顾了脑电图描述该脑电图发现的患者的病历,并记录了他们过去的医学和神经病学史,入院原因以及神经病学在入院和脑电图记录期间均处于状态。还对入院时的实验室检查结果以及伴随入院期间的EEG记录,计算机断层扫描或MRI发现进行了审查。评估了68位患者。性别比为1:1;平均年龄为56岁。慢性病发生在78%的患者中,包括高血压(34%),糖尿病(32%)和肾衰竭(18%)。入院时,肾衰竭(n = 34)和高血糖症(n = 22)最为突出。大多数患者至少有一项异常实验室检查结果。在脑电图过程中有意识水平的51例患者中有38例被描述为清醒状态。规定脑电图本底活动的58位患者中,超过一半表现出弥散性减慢,主要在theta范围内。 17例患者中有15例MRI异常。半球内病变,特别是缺血性和出血性病变最常见(n = 10),其次是基底神经节腔(n = 4)。在44例患者中有29例计算机断层扫描异常。半球状病理(弥漫性或局部性)发生在22例患者中。额叶间歇性节律性活动与轻度至中度脑病有关,主要在清醒患者中检测到。该系列的大多数患者患有慢性全身性疾病。旧的缺血性结构性脑损伤可能使某些患者在急性代谢紊乱(例如尿毒症和高血糖症)中易患FIRDA。额叶间歇节律性活动与脑电癫痫样活动无关。在这一系列FIRDA患者中未检测到深中线病变,后颅窝肿瘤和脑积水。

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