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首页> 外文期刊>Journal of child psychology and psychiatry >Editorial: Illuminating the dark matter of developmental neuropsychiatric genetics - Strategic focus for future research in child psychology and psychiatry
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Editorial: Illuminating the dark matter of developmental neuropsychiatric genetics - Strategic focus for future research in child psychology and psychiatry

机译:社论:照亮发育神经精神遗传学的暗物质-未来儿童心理学和精神病学研究的战略重点

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摘要

Research on genetic factors influencing cognitive and behavioural traits or which are central to the aetiology of neuropsychiatric diseases has been complicated by a furtive discrepancy between high heritability estimates and a scarcity of replicable gene-disorder associations. This 'missing heritability' has been either euphemised as the 'dark matter' of gene-trait association or aggravated as the looming crisis in behavioural genetics'. Nevertheless, in recognising the importance of this topic for our understanding of child psychiatric conditions and highlighting its commitment to the field, the Journal of Child Psychology and Psychiatry (JCPP) has for the first time appointed an editor with special responsibility for molecular (epi)genetics. This Editorial therefore aims to encourage submission of molecular genetic studies directly to JCPP by giving potential authors some effective guidelines for the design of (epi)genetic studies.
机译:由于遗传力高的估计值与可复制的基因-疾病关联的稀缺性之间的偷偷摸摸的差异,影响认知和行为特征或对神经精神疾病的病因至关重要的遗传因素的研究变得复杂了。这种“缺失的遗传性”要么被夸大为基因特征关联的“暗物质”,要么被加剧为即将出现的行为遗传学危机。尽管如此,在认识到该主题对于我们理解儿童精神病学状况的重要性并强调其对这一领域的承诺时,《儿童心理与精神病学杂志》(JCPP)首次任命了对分子(epi)负有特殊责任的编辑遗传学。因此,本社论旨在通过为潜在的作者提供一些设计(epi)遗传研究的有效指南,来鼓励直接向JCPP提交分子遗传研究。

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