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首页> 外文期刊>Journal of Clinical Ultrasound: JCU >Real-time ultrasound elastography in the diagnosis and differential diagnosis of subacute thyroiditis.
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Real-time ultrasound elastography in the diagnosis and differential diagnosis of subacute thyroiditis.

机译：实时超声弹性成像在亚急性甲状腺炎的诊断和鉴别诊断中。

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PURPOSE: To assess the value of real-time sonographic (US) elastography in the diagnosis of subacute thyroiditis (SAT). METHODS: This study included 29 lesions from 20 patients with SAT, 33 nodules from 24 patients with multinodular goiter, and 27 nodules from 23 patients with thyroid cancer. Eighty-nine lesions in these patients were examined by grayscale US and real-time US elastography. An elasticity score (ES), based on four classes of tissue stiffness (class 1 for soft lesions; class 2 and 3 for lesions intermediate in stiffness; class 4 for inelastic lesions), was introduced. The distribution of ESs for SAT and multinodular goiter or thyroid cancer was compared. Also, the correlation between serum-free thyroxine (FT4) concentrations and ESs for lesions in patients with SAT was analyzed. RESULTS: Nineteen of 29 SAT lesions had an ES of 3; the rest had an ES of 4. Of 33 multinodular goiter nodules, 5 had an ES of 1, 23 had an ES of 2, and 5 had an ES of 3. Eleven of 27 malignant thyroid nodules had an ES of 3; 15 had an ES of 4, and 1 had an ES of 2. In the distribution of ESs, there was a statistically significant difference between SAT lesions and multinodular goiter nodules (p < 0.05), but there was no significant difference between SAT lesions and malignant nodules (p > 0.05). No correlation existed between serum FT4 concentrations and ESs for the lesions in patients with SAT (p > 0.05). CONCLUSIONS: Real-time US elastography does not provide conclusive information in the diagnosis and differential diagnosis of SAT due to its inability to distinguish between SAT and thyroid cancer.
机译：目的：评估实时超声（US）弹性成像在诊断亚急性甲状腺炎（SAT）中的价值。方法：该研究包括来自20例SAT患者的29个病变，来自24例多结节性甲状腺肿的33个结节和来自23例甲状腺癌的27个结节。通过灰度US和实时US弹性成像检查了这些患者的89个病变。引入了基于四类组织刚度的弹性评分（ES）（对于软性病变为1级;对于中等硬度的病变为2级和3级;对于无弹性病变为4级）。比较了SAT和多结节性甲状腺肿或甲状腺癌的ES分布。此外，分析了无血清甲状腺素（FT4）浓度与ES患者病变的ESs之间的相关性。结果：29个SAT病变中有19个的ES为3。其余的ES为4。在33个多结节性甲状腺结节中，有5个的ES为1，23的ES为2，有的5的ES为3。27个恶性甲状腺结节中有11个的ES为3。 15的ES为4，1的ES为2。在ES的分布中，SAT病变与多结节性甲状腺肿结节之间存在统计学差异（p <0.05），但SAT病变与多发性甲状腺肿之间无统计学差异。恶性结节（p> 0.05）。 SAT患者的病灶中血清FT4浓度与ESs之间没有相关性（p> 0.05）。结论：由于无法区分SAT和甲状腺癌，实时美国弹性成像无法在SAT的诊断和鉴别诊断中提供结论性信息。

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