• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Clinical Ultrasound: JCU >Feasibility of semi-quantitative assessment of left ventricular contractile reserve in dilated cardiomyopathy
【24h】

Feasibility of semi-quantitative assessment of left ventricular contractile reserve in dilated cardiomyopathy

机译：半定量评估左心室收缩储备在扩张型心肌病中的可行性

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: We and others have shown previously that left ventricular (LV) contractile reserve assessed quantitatively by high-dose dobutamine stress-echocardiography (DSE) has prognostic implications in patients with dilated cardiomyopathy. Purpose: To assess the feasibility of semi-quantitative assessment of LV contractile reserve by differently skilled operators in patients with dilated cardiomyopathy. Methods: High-dose DSE was performed in 63 consecutive patients, mean age 50 ± 10 years and ejection fraction (EF) 19 ± 8%. LVEF was calculated 1) using Simpson's biplane formula, and 2) semi-quantitatively (5% increments) by novice and experienced echocardiographers, and by a DSE expert. Patients were considered to have preserved LV contractile reserve if LVEF dobutamine-induced change was ≥5%. Results: Twenty-seven (45.8%) patients died during the 5-year follow-up. The feasibility of the assessment was 89%, 94%, and 98% for novice and experienced readers and DSE expert, respectively. Kaplan-Meier analysis showed that LV contractile reserve assessed semi-quantitatively by DSE expert and experienced reader achieved the best prognostic separation (log rank 19.63 and 18.99, respectively, p < 0.001 for both), followed by quantitative assessment (log rank 9.76, p = 0.0018) and assessment by novice reader (log rank 8.76, p = 0.012). Areas under the curves were similar for quantitative and semi-quantitative assessment of LV contractile reserve. Conclusions: Our data indicate that semi-quantitative assessment of LV contractile reserve is feasible by differently skilled operators.
机译：背景：我们和其他人先前已经表明，通过大剂量多巴酚丁胺负荷超声心动图（DSE）定量评估的左心室（LV）收缩储备对扩张型心肌病患者的预后具有重要意义。目的：评估由不同技术的操作员对扩张型心肌病患者进行LV收缩储备半定量评估的可行性。方法：连续63例患者接受大剂量DSE，平均年龄50±10岁，射血分数（EF）为19±8％。 LVEF是1）使用Simpson的双翼飞机公式，2）由新手和经验丰富的超声心动图专家以及DSE专家半定量（增量为5％）计算得出的。如果LVEF多巴酚丁胺引起的变化≥5％，则认为患者已保留LV收缩储备。结果：在5年的随访中，有27名（45.8％）患者死亡。对于新手和有经验的读者以及DSE专家，评估的可行性分别为89％，94％和98％。 Kaplan-Meier分析显示，由DSE专家和经验丰富的读者半定量评估的LV收缩储备实现了最佳的预后分离（分别为log等级19.63和18.99，两者均p <0.001），随后是定量评估（log等级9.76，p）。 = 0.0018），并由新手阅读者进行评估（日志等级8.76，p = 0.012）。曲线下的面积用于LV收缩储备的定量和半定量评估是相似的。结论：我们的数据表明，不同技能的操作员可以对LV收缩储备进行半定量评估。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号