• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Clinical Ultrasound: JCU >Time course of cerebral hemodynamics in aneurysmal subarachnoid hemorrhage
【24h】

Time course of cerebral hemodynamics in aneurysmal subarachnoid hemorrhage

机译：动脉瘤性蛛网膜下腔出血的脑血流动力学的时程

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: Vascular complications are important causes of neurologic sequelae among survivors of aneurysmal subarachnoid hemorrhage (SAH). However, little is known about the time course of cerebral hemodynamics and outcome in patients with and without angiographically confirmed cerebral vasospasm. Methods.: Serial transcranial color-coded sonography (TCCS), angiography, and MRI studies were performed to measure cerebrovascular hemodynamics and assess complications following aneurysmal SAH. Results: Eighteen aneurysmal SAH patients were enrolled. Angiographically confirmed cerebral vasospasm occurred in 14 patients (77.8%), 5 of whom (35.7%) were asymptomatic. The mean blood flow velocity (V mean) of the middle cerebral artery increased significantly as compared with healthy volunteers from day 1 to day 15, and substantially decreased thereafter. The V mean of middle cerebral artery was significantly higher in patients with than in patients without angiographically confirmed cerebral vasospasm from day 3 to day 12. Compared to angiography, TCCS detected cerebral vasospasm with 85.7% sensitivity, 100% specificity, 100% positive predictive value, and 66.7% negative predictive value. MRI-evidenced cerebral infarctions occurred in nine patients (50%), three of whom (33.3%) were asymptomatic. Conclusions: This study demonstrated that approximately one-third of acute phase aneurysmal SAH patients have asymptomatic delayed cerebral infarction, which was undetected by TCCS in one-third of them. This may explain why the accuracy of TCCS to predict clinical symptomatic cerebral vasospasm is suboptimal.
机译：背景：血管并发症是动脉瘤性蛛网膜下腔出血（SAH）幸存者中神经系统后遗症的重要原因。然而，关于有或没有血管造影证实的脑血管痉挛的患者的脑血流动力学的时程和预后知之甚少。方法：进行了连续经颅彩色编码超声检查（TCCS），血管造影和MRI研究，以测量脑动脉血流动力学并评估SAH后的并发症。结果：18例动脉瘤SAH患者入组。经血管造影证实的脑血管痉挛发生在14例患者中（77.8％），其中5例（35.7％）无症状。从第1天到第15天，与健康志愿者相比，大脑中动脉的平均血流速度（V mean）显着增加，此后大幅下降。从第3天到第12天，有脑血管痉挛的患者比未经血管造影确诊的脑血管痉挛的患者的V均值显着更高。与血管造影相比，TCCS检测到的脑血管痉挛的敏感性为85.7％，特异性为100％，阳性预测值为100％ ，以及66.7％的负面预测值。 MRI证实的脑梗死发生在9例患者（50％）中，其中三例（33.3％）无症状。结论：这项研究表明，大约三分之一的急性期动脉瘤性SAH患者有无症状的延迟性脑梗塞，而其中的TCCS并未检测到这种延迟。这可以解释为什么TCCS预测临床症状性脑血管痉挛的准确性不佳。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号