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首页> 外文期刊>Clinical Biochemistry >Fasting plasma glucose versus glucose challenge test: screening for gestational diabetes and cost effectiveness.
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Fasting plasma glucose versus glucose challenge test: screening for gestational diabetes and cost effectiveness.

机译：空腹血糖与葡萄糖激发试验：筛查妊娠糖尿病和成本效益。

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Objective: To compare the performance in screening for gestational carbohydrate intolerance of the 1-h 50-g glucose challenge test (GCT), fasting plasma glucose (FPG) and fasting capillary glucose (FCG). Design and methods: FPG and FCG were measured at the same time as the GCT in 188 women. Gestational carbohydrate intolerance was diagnosed according to the Canadian Diabetes Association criteria. We constructed receiver operator characteristic (ROC) curves and compared the sensitivity and specificity of the FPG, FCG and GCT. Results: Gestational diabetes was diagnosed in 11.2% women and gestational impaired glucose tolerance in 8.4%. The areas under the ROC curves for the FPG, the GCT and the FCG were not statistically different (P = 0.26). The GCT yielded a better specificity than the FPG and the FCG for a comparable level of sensitivity. Conclusions: The GCT is better than the FPG in our population and is cost effective.
机译：目的：比较1小时50 g葡萄糖激发试验（GCT），空腹血浆葡萄糖（FPG）和空腹毛细血管葡萄糖（FCG）在筛查妊娠期碳水化合物耐受性方面的表现。设计和方法：在188名女性中，与GCT同时测量了FPG和FCG。妊娠期糖耐量不全是根据加拿大糖尿病协会的标准诊断的。我们构建了接收器操作员特征（ROC）曲线，并比较了FPG，FCG和GCT的灵敏度和特异性。结果：诊断为妊娠糖尿病的女性为11.2％，妊娠糖耐量为8.4％。 FPG，GCT和FCG的ROC曲线下面积无统计学差异（P = 0.26）。对于可比较的敏感性水平，GCT的特异性比FPG和FCG好。结论：在我们的人群中，GCT优于FPG，并且具有成本效益。

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