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首页> 外文期刊>Journal of clinical neuroscience: official journal of the Neurosurgical Society of Australasia >Low back pain and lumbar radiculopathy as harbingers of acute myeloid leukemia recurrence in a patient with myeloid sarcoma
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Low back pain and lumbar radiculopathy as harbingers of acute myeloid leukemia recurrence in a patient with myeloid sarcoma

机译：下腰痛和腰椎神经根病是髓样肉瘤患者急性髓样白血病复发的预兆

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摘要

Myeloid sarcoma (MS) is an extra-osseous, solid collection of myeloblasts. It is associated with myeloid leukemias, and rarely affects the spine. The most common clinical presentation of MS in spine patients is some form of pain related to compression of neural elements. Given that MS is rare, and its imaging characteristics are similar to other more common diagnoses, it is frequently missed on initial presentation. We present a 28-year-old female, in her fifth year of remission from AML, with low back pain and right lumbar radiculopathy. Initially, the leading diagnosis was schwannoma in preference to neurofibroma; however, intra-operative pathology and subsequent bone marrow biopsy revealed the tumor to be MS. This report highlights the difficulties of diagnosis of MS in patients in remission from acute myeloid leukemia. Thus, in patients with a history of leukemia, MS should be considered in the differential diagnosis of any epidural or nerve root tumor. Timely diagnosis and treatment are key to optimal outcomes.
机译：髓样肉瘤（MS）是骨外的，坚固的成肌细胞集合。它与髓样白血病相关，很少影响脊柱。脊柱患者MS的最常见临床表现是某种形式的与神经元受压有关的疼痛。鉴于MS罕见，并且其影像学特征与其他更常见的诊断相似，因此在初次出现时经常会漏诊。我们介绍了一位28岁的女性，在她从AML康复的第五年中，腰痛和右腰神经根病。最初，主要诊断是神经鞘瘤优先于神经纤维瘤。然而，术中病理及随后的骨髓活检显示该肿瘤为MS。该报告强调了急性髓细胞性白血病缓解的患者诊断MS的困难。因此，在有白血病史的患者中，在任何硬膜外或神经根肿瘤的鉴别诊断中应考虑MS。及时的诊断和治疗是获得最佳结果的关键。

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