A 42-year-old woman was taken to hospital with a 3-day history of progressive confusion and agitation. On observation, she was mute and displayed significant immobility.At times, the immobility was accompanied by catalepsy or "waxy flexibility". There was no obvious evidence of focal neurological deficits.An MRI of the head revealed numerous white matter mass-like lesions (Fig. 1). Other investigations, including cerebrospinal fluid (CSF) analysis were normal.
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