Pilocytic astrocytoma with neoplastic gemistocytes undergoing spontaneous transformation to glioblastoma multiforme without prior radiotherapy.

Privett BJ; Liubinas SV; Tsui A; Gonzales M; Lo P

首页> 外文期刊>Journal of clinical neuroscience: official journal of the Neurosurgical Society of Australasia >Pilocytic astrocytoma with neoplastic gemistocytes undergoing spontaneous transformation to glioblastoma multiforme without prior radiotherapy.

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Pilocytic astrocytoma with neoplastic gemistocytes undergoing spontaneous transformation to glioblastoma multiforme without prior radiotherapy.

机译：恶性星形胶质细胞的恶性星形细胞瘤无需事先放疗即可自发转化为多形性胶质母细胞瘤。

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Pilocytic astrocytoma, the most common glioma of childhood, is considered a clinically benign tumour. Malignant transformation of this tumour is rare and thought to occur almost exclusively in the setting of prior radiotherapy. We describe a patient with mixed pilocytic and gemistocytic astrocytoma which transformed into a glioblastoma multiforme, leading to rapid deterioration and death of the patient, without prior radiotherapy.

机译：小儿星形胶质细胞瘤是儿童期最常见的神经胶质瘤，被认为是一种临床良性肿瘤。这种肿瘤的恶性转化是罕见的，并且被认为几乎仅在先前的放射疗法中发生。我们描述了一个混合的细胞性星形胶质细胞瘤和双核细胞性星形细胞瘤的患者，该患者转化为多形性胶质母细胞瘤，导致患者快速恶化和死亡，而无需事先放疗。

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《Journal of clinical neuroscience: official journal of the Neurosurgical Society of Australasia》 |2011年第5期|共3页
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Privett BJ; Liubinas SV; Tsui A; Gonzales M; Lo P;
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中图分类神经病学与精神病学;
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1. Pilocytic astrocytoma with neoplastic gemistocytes undergoing spontaneous transformation to glioblastoma multiforme without prior radiotherapy. [J] . Privett BJ, Liubinas SV, Tsui A, Journal of clinical neuroscience: official journal of the Neurosurgical Society of Australasia . 2011,第5期

机译：恶性星形胶质细胞的恶性星形细胞瘤无需事先放疗即可自发转化为多形性胶质母细胞瘤。
2. Secondary Glioblastoma Multiforme in a Child with Disseminated Juvenile Pilocytic Astrocytoma [J] . C. S.Amene, L. A.Yeh-Nayre, J. R.Crawford Case Reports in Oncological Medicine . 2012,第1期

机译：继发性胶质母细胞瘤多发性儿童少年星形胶质细胞瘤。
3. Genetic evidence of the neoplastic nature of gemistocytes in astrocytomas [J] . Rui M. Reis, Akira Hara, Paul Kleihues, Acta Neuropathologica . 2001,第5期

机译：星形细胞瘤中双核细胞的肿瘤性质的遗传证据
4. Octreotide Reduces Malignant Potential of Glioblastoma Multiforme to the Level of Low Grade Astrocytomas - Clinical Study [C] . I. Stefanovic, M. Babic, V. Katie European Congress of Neurosurgery . 2003

机译：奥雷妥氧化物可降低胶质母细胞瘤的恶性潜力，以低级星形细胞瘤水平 - 临床研究
5. Aberrant Signaling in Astrocytomas and Glioblastoma Multiforme (GBM): Utilizing Inhibitors of Proliferation as Potential Therapies. [D] . Connell-Albert, Yvette S. 2013

机译：星形细胞瘤和胶质母细胞瘤（GBM）中的异常信号：利用增殖抑制剂作为潜在疗法。
6. Secondary Glioblastoma Multiforme in a Child with Disseminated Juvenile Pilocytic Astrocytoma [O] . C. S. Amene, L. A. Yeh-Nayre, J. R. Crawford 2012

机译：继发性胶质母细胞瘤多发性儿童少年星形胶质细胞瘤。
7. Synchronous pediatric supratentorial glioblastoma multiforme with noncontiguous infratentorial pilocytic astrocytoma: A rare event [O] . Jitender Chaturvedi, Bevinahalli N Nandeesh, Dwarakanath Srinivas, 2016

机译：同期小儿幕上多形性胶质母细胞瘤与不连续的幕下毛细胞星形细胞瘤：罕见事件
8. Human Bronchial Epithelial Cell Strain with Unusual In vitro Growth Potential Which Undergoes Neoplastic Transformation after SV40 T Antigen Gene Transfection. [R] . Reddel, R. R., Hsu, I. C., Mass, M. J., 1991

机译：sV40 T抗原基因转染后具有异常体外生长潜力的人支气管上皮细胞株的肿瘤转化。

Pilocytic astrocytoma with neoplastic gemistocytes undergoing spontaneous transformation to glioblastoma multiforme without prior radiotherapy.

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