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首页> 外文期刊>Journal of cataract and refractive surgery >Corneal lenticule harvest using a microkeratome and an artificial anterior chamber system at high intrachamber pressure.
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Corneal lenticule harvest using a microkeratome and an artificial anterior chamber system at high intrachamber pressure.

机译：在高腔内压力​​下使用微角膜刀和人工前房系统收获角膜微孔。

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摘要

PURPOSE: To evaluate the safety and accuracy of a manual microkeratome and an artificial anterior chamber used at high intrachamber pressure to harvest corneal lenticules for lamellar keratoplasty. SETTING: Department of Ophthalmology, University of California, Irvine, California, USA. METHODS: Forty-seven human eye-bank corneoscleral rims were mounted on an artificial anterior chamber. A manual microkeratome was used to perform lamellar keratectomy at a mean intrachamber pressure of 95.8 mm hg +/- 4.8 (sd). Two thicknesses (300 microm and 360 microm microkeratome heads) and diameters (8.0 mm and 9.0 mm) were attempted, and the resultant lenticules were analyzed by pachymetry and digital photography. RESULTS: In the 9.0 mm/360 microm group, corneal perforation occurred in 12 of 17 lenticules (71.2%). Except for this group, 24 of 30 corneas (80.0%) showed a less than 0.5 mm deviation from the expected diameter. Neither the horizontal nor the vertical diameter differences were statistically significant (P >.05). The difference between the horizontal and vertical diameters was within +/-0.2 mm in 23 corneas (76.7%). Three (10.0%) corneal beds contained a slightly uneven keratectomy margin. CONCLUSIONS: This system provided accurate and smooth lenticules for lamellar keratoplasty. The precision and accuracy of the obtained corneal lenticules were better than those in previous reports. However, the 9.0 mm diameter/360 microm thickness head with high intrachamber pressure should not be applied in the clinical setting without further testing. In this laboratory study, a minimal corneal thickness of 588 microm was required to avoid perforation.
机译：目的：评估手动微型角膜刀和人工前房的安全性和准确性，该人工前角膜腔和人工前房用于高腔内压力​​以收集角膜微孔用于层状角膜移植术。地点：美国加州大学欧文分校眼科。方法：将47只人类眼库角膜巩膜边缘安装在人工前房上。使用手动微型角膜刀在平均室腔内压力为95.8 mm hg +/- 4.8（sd）的条件下进行板状角膜切除术。尝试了两种厚度（300微米和360微米的微型角膜刀头）和直径（8.0毫米和9.0毫米），并通过测厚法和数字摄影对所得的微透镜进行了分析。结果：9.0 mm / 360 microm组中，在17个小透镜中的12个中有7个（71.2％）发生了角膜穿孔。除该组外，30个角膜中的24个（80.0％）与预期直径的偏差小于0.5 mm。水平直径和垂直直径的差异均无统计学意义（P> .05）。在23个角膜中，水平直径和垂直直径之间的差异在+/- 0.2毫米之内（76.7％）。三张（10.0％）角膜病床的角膜切除切缘略微不均匀。结论：该系统为板状角膜移植术提供了准确而光滑的小透镜。所获得的角膜微透镜的精确度和准确性优于以前的报道。但是，如果没有进一步测试，则不应在临床环境中使用直径为9.0毫米/ 360微米厚的腔室内高压力头。在此实验室研究中，为避免穿孔，要求最小角膜厚度为588微米。

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