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首页> 外文期刊>Journal of computer assisted tomography >Chronic pulmonary thromboembolism. Air trapping on computed tomography and correlation with pulmonary function tests.
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Chronic pulmonary thromboembolism. Air trapping on computed tomography and correlation with pulmonary function tests.

机译：慢性肺血栓栓塞症。计算机断层扫描上的空气捕获，并与肺功能测试相关。

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OBJECTIVE: We evaluated lung attenuation on inspiratory/expiratory computed tomography (CT) and spiral CT angiography (CTA) from patients with chronic pulmonary embolism and correlated the CT findings with pulmonary function test (PFT) results. METHODS: We retrospectively reviewed 9 patients with chronic embolism (mean age, 62.3 years; 5 women and 4 men). Paired inspiratory, expiratory CT and matching CTA images were reviewed, and lung attenuation was evaluated in each segment. Lower attenuation on inspiratory images and air trapping on expiratory images were subjectively assessed and correlated with PFT results. The relationship between the presence of clot and lung attenuation was evaluated. Nine age-matched normal subjects served as controls. RESULTS: Lower attenuation with mosaic perfusion and air trapping were identified in 6 and 9 patients, respectively (mean scores, 8.1 and 11.3, respectively). Air trapping was identified in 19 (42.2%) of 45 segments with lower attenuation on inspiratory images,but was also noted in 31 segments with normal inspiratory attenuation. Air trapping was associated with the presence of proximal arterial stenosis (P<0.01), and the area showed less contrast enhancement than the adjacent lung (P<0.05). Extent of air trapping correlated inversely with PFT parameters of peripheral airway obstruction such as maximum mid-expiratory flow rate (r=-0.86, P=0.003). On the other hand, extent of mosaic perfusion did not correlate with PFT. CONCLUSIONS: Air trapping is commonly seen in chronic embolism and is found in areas of relative hypoperfusion. The extent of air trapping correlates with parameters of peripheral airway obstruction.
机译：目的：我们评估了慢性肺栓塞患者的吸气/呼气计算机断层扫描（CT）和螺旋CT血管造影（CTA）的肺衰减，并将CT表现与肺功能检查（PFT）结果相关。方法：我们回顾性研究了9例慢性栓塞患者（平均年龄62.3岁; 5名女性和4名男性）。回顾了成对的吸气，呼气CT和匹配的CTA图像，并评估了每个节段的肺衰减。主观评估吸气图像上的较低衰减和呼气图像上的空气滞留，并将其与PFT结果相关。评价了血块的存在与肺衰减之间的关系。九名年龄匹配的正常受试者作为对照。结果：分别在6例和9例患者中发现了镶嵌灌注和空气滞留引起的衰减降低（平均评分分别为8.1和11.3）。在吸气图像上衰减较低的45个段中，有19个（42.2％）出现空气滞留，但在吸气衰减正常的31个段中也发现了空气滞留。空气滞留与近端动脉狭窄的存在有关（P <0.01），并且该区域显示出的对比度增强程度少于相邻肺（P <0.05）。空气滞留的程度与周围气道阻塞的PFT参数成反比，如最大呼气中期流量（r = -0.86，P = 0.003）。另一方面，镶嵌灌注的程度与PFT无关。结论：空气阻塞在慢性栓塞中很常见，并且在相对灌注不足的区域也可见。空气滞留的程度与周围气道阻塞的参数有关。

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