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首页> 外文期刊>Journal of computer assisted tomography >Primary dedifferentiated liposarcoma of the retroperitoneum. Prognostic significance of computed tomography and magnetic resonance imaging features.
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Primary dedifferentiated liposarcoma of the retroperitoneum. Prognostic significance of computed tomography and magnetic resonance imaging features.

机译：腹膜后原发性去分化脂肪肉瘤。计算机断层扫描和磁共振成像特征的预后意义。

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OBJECTIVES: To describe computed tomography (CT) and magnetic resonance (MR) imaging findings and to determine the prognostic significance of radiologic appearances in primary dedifferentiated liposarcoma of the retroperitoneum. METHODS: Initial CT and MR imaging studies of 20 pathologically confirmed cases of primary dedifferentiated liposarcoma of the retroperitoneum were retrospectively reviewed and assessed for correlations with the histopathologic features. CT and MR images were evaluated by 2 radiologists with agreement by consensus, and univariate analyses were conducted to evaluate survival with a mean clinical follow-up duration of 47 months (range, 5-114 months). RESULTS: Tumor invasion was more frequent in the anterior or posterior pararenal originating tumors than in pararenal tumors (P<0.05). Well-defined nonlipomatous masses juxtaposed with fatty tumors were identified in all cases. Calcification or ossification was seen in 6 patients (30%) on unenhanced CT. Imaging findings including attenuation, signal characteristics, and enhancement patterns of nonlipomatous masses were nonspecific regardless of histologic variances. Recurrent tumors (n=6) tended to invade surrounding organs. Univariate analysis revealed that calcification or ossification (P<0.05) and first recurrence with duration of a mean 13 months (P<0.05) identified by imaging studies had significant impacts on overall survival. CONCLUSIONS: Calcification or ossification and first recurrence identified by CT and MR imaging studies are significant adverse prognostic factors in primary dedifferentiated liposarcoma of the retroperitoneum.
机译：目的：描述计算机断层扫描（CT）和磁共振成像（MR）的影像学发现，并确定腹膜后原发性去分化脂肪肉瘤的影像学表现对预后的意义。方法：回顾性地回顾性分析了20例经病理证实的腹膜后原发性去分化脂肪肉瘤的CT和MR影像学，并评估其与组织病理学特征的相关性。两名放射科医生在达成共识的情况下对CT和MR图像进行了评估，并进行了单因素分析以评估生存率，平均临床随访时间为47个月（5-114个月）。结果：肾前旁或后肾源性肿瘤的肿瘤浸润发生率高于肾旁癌（P <0.05）。在所有病例中均发现了明确定义的并发脂肪瘤的非脂肪性肿块。未经增强CT检查的6例患者（30％）出现钙化或骨化。不论组织学差异如何，包括非脂瘤性肿块的衰减，信号特征和增强模式在内的影像学检查结果都是非特异性的。复发性肿瘤（n = 6）倾向于侵袭周围器官。单因素分析显示，影像学检查发现钙化或骨化（P <0.05）和首次复发（平均13个月）（P <0.05）对总体生存率有显着影响。结论：钙化或骨化以及CT和MR影像学检查发现的首次复发是腹膜后原发性去分化脂肪肉瘤的重要不良预后因素。

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