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首页> 外文期刊>Journal of chromatography, A: Including electrophoresis and other separation methods >Analytical methods for monitoring contaminants in food-An industrial perspective
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Analytical methods for monitoring contaminants in food-An industrial perspective

机译：监测食品中污染物的分析方法-工业视角

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Incoming legislation on the registration, evaluation, authorisation and restriction of chemical substances places responsibility on the chemical industry, including downstream users of chemicals, to provide appropriate safety information with which to improve the protection of human health and the environment through the better and earlier identification of the intrinsic properties of chemical substances. Food consumption is only one of several potential exposure routes, but if industrial chemicals enter the food chain. the diet may be a significant pathway of human exposure. Consequently strong measures are taken to protect the integrity of the human food chain and these are constantly revised to address perceived chemical safety threats. In order to understand the risk presented by the possible presence of a chemical residue in food, knowledge is required of its toxicology and of the level of exposure. Reliable exposure assessment requires robust analytical methodology. Existing standards for the validation and performance evaluation of methods have led to improved analytical capability and better inter-laboratory agreement of results. However, increasing the availability of robust, cost-effective methodology should be the benchmark for future developments in the field of food chemical residue analysis. Chromatography meets the needs of target analyses well and largely provides the selectivity of measurement needed to assess compliance with food regulatory limits. However, to keep pace with the increased need for expanded analytical capability - faster throughput, more analytes per sample - chromatographic separation capability still needs to grow. In this respect, orthogonal separation techniques and multi-dimensional chromatography are key tools for the future. (C) 2008 Elsevier B.V. All rights reserved.
机译：即将颁布的有关化学物质的注册，评估，授权和限制的法律赋予化学工业（包括化学物质的下游用户）责任，以提供适当的安全信息，从而通过更好地及早识别来改善对人类健康和环境的保护化学物质的固有特性。食物消费只是几种潜在的接触途径之一，但是如果工业化学品进入食物链。饮食可能是人体暴露的重要途径。因此，采取了强有力的措施来保护人类食物链的完整性，并不断对其进行修订以应对感知到的化学安全威胁。为了了解食物中可能存在化学残留物带来的风险，需要了解其毒理学和暴露水平。可靠的暴露评估需要强大的分析方法。现有方法验证和性能评估标准提高了分析能力，并在实验室之间取得了更好的结果一致性。但是，增加健壮，具有成本效益的方法的可用性应成为食品化学残留物分析领域未来发展的基准。色谱法很好地满足了目标分析的需求，并在很大程度上提供了评估是否符合食品法规限制所需的测量选择性。但是，为了跟上对扩展分析能力不断增长的需求-更快的通量，每个样品更多的分析物-色谱分离能力仍然需要增长。在这方面，正交分离技术和多维色谱是未来的关键工具。 （C）2008 Elsevier B.V.保留所有权利。

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