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首页> 外文期刊>Journal of dietary supplements >Effect of Four Weeks of /3-alanine Supplementation on Muscle Carnosine and Blood Serum Lactate during Exercise in Male Rats
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Effect of Four Weeks of /3-alanine Supplementation on Muscle Carnosine and Blood Serum Lactate during Exercise in Male Rats

机译：补充四周/ 3-丙氨酸对雄性大鼠运动过程中肌肌肽和血乳酸的影响

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摘要

Beta-alanine (BA) supplementation may increase muscle buffering capacity and affect physiological responses during exercise. We examined the effects of 4 weeks of BA supplementation on muscle camosine and serum lactate in male rats. Rats (n = 24, age:2 months, body weight: 265±22 g) were divided into a BA supplementation or control group. Along with aerobic acclimatization exercise (15 mmin"1, 8-10 minday1,4 days-week 1 for 4 weeks), the BA group had access to BA powder in their drinking water (1.8%) with the control group having access to plain water for 4 weeks. After 4 weeks, rats ran on a treadmill at speeds of 15,20,25,30, and 35 mmin1, respectively, each for 4 min, in order to measure post-exercise serum lactate. Muscle carnosine and serum lactate levels were measured with high-performance liquid chromatography (HPLC) and enzyme-linked immunosorbant assay (ELISA) procedures, respectively. Following BA supplementation, carnosine content in the m. rectus femoris increased by 117% (p < .01) and serum lactate decreased by 7.4% (p < .01). It was concluded that ^-alanine supplementation increases muscle carnosine content and reduces serum lactate; these changes may indicate an adaptation of rat skeletal muscles to postpone peripheral muscle fatigue during high-intensity exercise.
机译：补充β-丙氨酸（BA）可能会增加肌肉缓冲能力，并影响运动过程中的生理反应。我们检查了补充BA 4周对雄性大鼠肌肉肌氨酸和血清乳酸的影响。将大鼠（n = 24，年龄：2个月，体重：265±22 g）分为BA补充组或对照组。除了有氧适应训练（15 mmin“ 1，第8-10分钟，每天1,4天，第1周，共4周），BA组可以使用饮用水中的BA粉（1.8％），而对照组则可以使用纯净水。水运动4周，4周后，大鼠分别在跑步机上分别以15、20、25、30和35 mmin1的速度跑步4分钟，以测量运动后的血清乳酸。乳酸水平分别通过高效液相色谱（HPLC）和酶联免疫吸附测定（ELISA）程序进行测量，补充BA后，股直肌中肌肽的含量增加了117％（p <.01）乳酸减少了7.4％（p <.01）。结论是，补充^-丙氨酸可增加肌肉肌肽含量并降低血清乳酸;这些变化可能表明大鼠骨骼肌对高强度运动中外周肌肉疲劳的适应性降低。

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