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首页> 外文期刊>Journal of cutaneous pathology >A histopathologic study of arthropod bite reactions in 20 patients highlights relevant adnexal involvement.
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A histopathologic study of arthropod bite reactions in 20 patients highlights relevant adnexal involvement.

机译：对20例节肢动物叮咬反应的组织病理学研究突出显示了相关的附件受累。

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摘要

BACKGROUND: Insect bites produce diverse skin reactions. Although quite common, the histopathologic features of arthropod assaults have not ever been studied systemically. MATERIALS AND METHODS: Twenty biopsies from cases, clinically diagnosed as arthropod bite reactions between January 2003 and June 2007 were reviewed retrospectively. The aim of the study was to verify as to whether reliable histopathologic criteria could be established based on the frequency of findings observed. RESULTS: Epidermal spongiosis (present in 16 of 20 cases), in particular spongiosis of the infundibular epithelium and acrosyringia as well as eosinophilic spongiosis, emerge as relevant diagnostic clues. A moderately dense, superficial and deep infiltrate consisting mainly of lymphocytes and eosinophils was prevalent in the dermis, with eosinophils tending to interstitial and periadnexal distribution. Of note, 19 of 20 (95%) cases revealed periadnexal involvement, whereas 16 of 20 (80%) had the infiltrate extending particularly along the sweat ducts and the coiled glands. In three biopsies, concomitant involvement of sweat glands, hair follicles and sebaceous glands was noted. CONCLUSION: A practical histopathologic algorithm of arthropod bite recognition is proposed. The involvement of the sweat glands in the pattern of arthropod bite reaction is suggested as a new reliable diagnostic clue.
机译：背景：昆虫叮咬会产生多种皮肤反应。尽管很普遍，但节肢动物袭击的组织病理学特征尚未得到系统的研究。材料与方法：回顾性分析了2003年1月至2007年6月间临床诊断为节肢动物叮咬反应的病例的20例活组织检查。该研究的目的是根据观察到的结果的频率来验证是否可以建立可靠的组织病理学标准。结果：表皮海绵状变性（目前占20例中的16例），尤其是漏斗上皮和肩突炎的海绵状以及嗜酸性海绵状海绵化，成为相关的诊断线索。真皮中普遍存在中等密度，浅表和深层浸润，主要由淋巴细胞和嗜酸性粒细胞组成，嗜酸性粒细胞趋于间质和肾上腺分布。值得注意的是，20例中的19例（95％）表现为肾上腺受累，而20例中的16例（80％）浸润尤其是沿着汗管和盘绕的腺体延伸。在三个活检中，注意到汗腺，毛囊和皮脂腺同时受累。结论：提出了一种实用的节肢动物咬伤识别的组织病理学算法。汗腺参与节肢动物叮咬反应的模式被认为是一种新的可靠诊断线索。

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