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首页> 外文期刊>Journal of cutaneous pathology >Believe it or not: A truism or an entrenched paradigm?
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Believe it or not: A truism or an entrenched paradigm?

机译:信不信由你:现实主义或根深蒂固的范式?

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摘要

Whether one is a full-bore dysplasticist who believes without question that melanocytic nevi progress gradually through increasing dysplasia and atypia with eventuation as melanoma at one pole, whether one is a fanatical Ackerman clone who views the histopathologic interpretation and oncogenesis of melanocytic tumors much like a light switch (it's either on or off, yes or no, melanoma or not) at the other, or whether one falls somewhere between those extremes, dermatopathologists of any stripe can agree that requisition forms bearing a clinical context of rule out dysplasia or mle out atypia are exceedingly common in the laboratory and that a sizable proportion of each diagnostic day is spent deliberating whether given biopsy specimens demonstrate utterly conventional melanocytic nevi, dysplastic/Clark/atypical melanocytic nevi, or melanoma.
机译:是否有人是全口异型增生专家,他毫无疑问地认为黑素细胞痣会通过增加异型增生和异型性病而逐渐发展,并最终发展为一极黑色素瘤,是否有人是狂热的Ackerman克隆者,对黑素细胞瘤的组织病理学解释和致癌作用的看法与另一个的电灯开关(开或关,是或否,黑色素瘤的发生与否),或者一个开关是否落在这些极端之间,任何条带的皮肤病理学家都可以同意,具有临床上排除不典型增生或m灭的请购单非典型性异常在实验室中极为普遍,每个诊断日都要花费相当多的时间来考虑是否给定的活检标本显示出完全常规的黑素细胞痣,增生/克拉克/非典型性黑素细胞痣或黑色素瘤。

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