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首页> 外文期刊>Journal of experimental & clinical cancer research : >Outcome after treatment of papillary thyroid microcarcinoma.
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Outcome after treatment of papillary thyroid microcarcinoma.

机译：甲状腺乳头状微癌治疗后结果。

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Patients with thyroid microcarcinoma (TMC) have favourable long-term prognoses. However, recurrences in the neck and distant metastases have been reported. The authors investigated independent factors associated with recurrence in an effort to define therapeutic guidelines. In this study they report the results of a retrospective review of patients followed at one Institution. 120 patients ( 96 females and 24 males; mean age 45.2 years) with a papillary thyroid microcarcinoma (PTC) < or =1 cm in greatest dimension were analyzed. All of them were followed for 5 to 15 years. 106 of them were managed aggressively (total thyroidectomy), the remainder treated with lobectomy alone. Radioiodine therapy was performed in 62/106 patients submitted to total thyroidectomy. Despite the different treatment and the presence of neck node metastases at the time of the diagnosis in 26 of the reported 120 patients (22%) and local invasion beyond the thyroid capsule in 20 (17%), only 1.7% of patients had neck nodal local recurrence. No patient died or developed distant metastases. In this preliminary study the authors conclude that the outcome of PMC is generally favourable, even in presence of lymph-node metastases and local invasion, independently of the primary treatment.
机译：甲状腺微癌（TMC）患者具有良好的长期预后。然而，已经报道了颈部复发和远处转移。作者研究了与复发相关的独立因素，以定义治疗指南。在这项研究中，他们报告了对一所机构的患者进行回顾性回顾的结果。分析了最大尺寸为乳头状甲状腺微癌（PTC）<或= 1 cm的120例患者（96例女性和24例男性;平均年龄45.2岁）。他们都被追踪了5到15年。其中106例被积极治疗（全甲状腺切除术），其余仅用肺叶切除术治疗。接受全甲状腺切除术的62​​/106例患者接受了放射性碘治疗。尽管有不同的治疗方法，并且在报告的120例患者中有26例在诊断时存在颈部淋巴结转移（22％），而甲状腺包膜以外的局部浸润在20例中（17％），但只有1.7％的患者有颈部淋巴结局部复发。没有患者死亡或发生远处转移。在这项初步研究中，作者得出的结论是，即使存在淋巴结转移和局部浸润，PMC的治疗结果通常也是有利的，而与主要治疗无关。

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