Thiourea inhibitors of herpes viruses. part 1: bis-(aryl)thiourea inhibitors of CMV.

Bloom JD; DiGrandi MJ; Dushin RG; Curran KJ; Ross AA; Norton EB; Terefenko E; Jones TR; Feld B; Lang SA

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Thiourea inhibitors of herpes viruses. part 1: bis-(aryl)thiourea inhibitors of CMV.

机译：疱疹病毒的硫脲抑制剂。第1部分：CMV的双-（芳基）硫脲抑制剂。

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Bis-(aryl)thioureas were found to be potent and selective inhibitors of cytomegalovirus (CMV) in cultured HFF cells. Of these, the thiazole analogue 38 was investigated as a potential development candidate.

机译：发现双（芳基）硫脲是培养的HFF细胞中巨细胞病毒（CMV）的有效和选择性抑制剂。其中，噻唑类似物38被研究为潜在的开发候选物。

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《Bioorganic and Medicinal Chemistry Letters》 |2003年第17期|共4页
作者
Bloom JD; DiGrandi MJ; Dushin RG; Curran KJ; Ross AA; Norton EB; Terefenko E; Jones TR; Feld B; Lang SA;
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正文语种 eng
中图分类基础医学;
关键词
inhibitors; Thiourea; cisplatin/methotrexate/vinblastine; Viral; Herpes NOS; 硫脲;

机译：抑制剂;硫脲;顺铂/甲氨蝶呤/长春碱;病毒;疱疹NOS;硫脲;

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专利

1. Thiourea inhibitors of herpes viruses. part 1: bis-(aryl)thiourea inhibitors of CMV. [J] . Bloom JD, DiGrandi MJ, Dushin RG, Bioorganic and Medicinal Chemistry Letters . 2003,第17期

机译：疱疹病毒的硫脲抑制剂。第1部分：CMV的双-（芳基）硫脲抑制剂。
2. Synthesis of sulfadiazinyl acyl/aryl thiourea derivatives as calf intestinal alkaline phosphatase inhibitors, pharmacokinetic properties, lead optimization, Lineweaver-Burk plot evaluation and binding analysis [J] . Sajid-ur-Rehman, Saeed Aamer, Saddique Gufran, Bioorganic and medicinal chemistry . 2018,第12期

机译：作为小牛肠碱性磷酸酶抑制剂，药代动力学性能，铅优化，LINEWEAVER-BROK评估和结合分析的合成
3. Synthesis, computational studies and biological evaluation of new 1-acetyl-3-aryl thiourea derivatives as potent cholinesterase inhibitors [J] . Saeed Aamer, Shah Muhammad Shakil, Larik Fayaz Ali, Medicinal chemistry research: an international journal for rapid communications on design and mechanisms of action of biologically active agents . 2017,第8期

机译：新的1-乙酰基-3-芳基硫脲衍生物作为有效的胆碱酯酶抑制剂的合成，计算研究和生物学评价
4. Thiourea Derivatives as Steel Corrosion Inhibitors: Density Functional Theory and Experimental Studies [C] . Venkata Muralidhar K, Vinay Jain, Beena Rai NACE international corrosion conference and expo . 2019

机译：硫脲衍生物作为钢的缓蚀剂：密度泛函理论和实验研究
5. Synthesis and Characterization of Platinum(II) Ethylenediamine Complexes with Thiourea-like Ligands [D] . Bahkali, Ashwaq. 2020

机译：用硫脲样配体的铂（II）乙二胺配合物的合成与表征
6. Novel Class of Thiourea Compounds That Inhibit Herpes Simplex Virus Type 1 DNA Cleavage and Encapsidation: Resistance Maps to the UL6 Gene [O] . Marja van Zeijl, Jeanette Fairhurst, Thomas R. Jones, 2000

机译：抑制单纯疱疹病毒1型DNA切割和衣壳化的新型硫脲类化合物：对UL6基因的抗性图
7. Novel Class of Thiourea Compounds That Inhibit Herpes Simplex Virus Type 1 DNA Cleavage and Encapsidation: Resistance Maps to the UL6 Gene [O] . van Zeijl, Marja, Fairhurst, Jeanette, Jones, Thomas R., 2000

机译：抑制单纯疱疹病毒1型DNA切割和衣壳化的新型硫脲类化合物：对UL6基因的抗性图

Thiourea inhibitors of herpes viruses. part 1: bis-(aryl)thiourea inhibitors of CMV.

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