Acetylcholinesterase noncovalent inhibitors based on a polyamine backbone for potential use against Alzheimer's disease.

Melchiorre C; Andrisano V; Bolognesi ML; Budriesi R; Cavalli A; Cavrini V; Rosini M; Tumiatti V; Recanatini M

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Acetylcholinesterase noncovalent inhibitors based on a polyamine backbone for potential use against Alzheimer's disease.

机译：基于多胺骨架的乙酰胆碱酯酶非共价抑制剂，可潜在地对抗阿尔茨海默氏病。

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来源
《Journal of Medicinal Chemistry》 |1998年第22期|共4页
作者
Melchiorre C; Andrisano V; Bolognesi ML; Budriesi R; Cavalli A; Cavrini V; Rosini M; Tumiatti V; Recanatini M;
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正文语种 eng
中图分类药学;
关键词
Alzheimer Disease drug therapy; Cholinesterase Inhibitors; Polyamines; Butyrylcholinesterase; 胆碱酯酶抑制剂; 聚胺类;

机译：Alzheimer Disease drug therapy;Cholinesterase Inhibitors;Polyamines;Butyrylcholinesterase;胆碱酯酶抑制剂;聚胺类;

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专利

1. Acetylcholinesterase noncovalent inhibitors based on a polyamine backbone for potential use against Alzheimer's disease. [J] . Melchiorre C, Andrisano V, Bolognesi ML, Journal of Medicinal Chemistry . 1998,第22期

机译：基于多胺骨架的乙酰胆碱酯酶非共价抑制剂，可潜在地对抗阿尔茨海默氏病。
2. Structure-Activity Relationships of Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone.3.Effect of Replacing the Inner Polymethylene Chain with Cyclic Moieties [J] . Vincenzo Tumiatti, Vincenza Andrisano, Rita Banzi Journal of Medicinal Chemistry . 2004,第26期

机译：基于多胺骨架的乙酰胆碱酯酶非共价抑制剂的结构-活性关系3.用环部分取代多亚甲基内链的作用
3. Structure-Activity Relationships of Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone. 2. Role of the Substituents on the Phenyl Ring and Nitrogen Atoms of Caproctamine [J] . Vincenzo Tumiatti, Michela Rosini, Manuela Bartolini, Journal of Medicinal Chemistry . 2003,第6期

机译：基于多胺主链的乙酰胆碱酯酶非共价抑制剂的结构活性关系。 2.取代基对卡帕他敏的苯环和氮原子的作用
4. A new strategy to combat Alzheimer's disease. Combining radical-scavenging potential with metal-protein-attenuating ability in one molecule [C] . Hong-Fang Ji, Hong-Yu Zhang 第二届全国分子模拟与信息技术软件应用研讨会暨第四届创腾科技用户大会 . 2005

机译：对抗阿尔茨海默氏病的新策略。在一分子中将自由基清除潜能与金属蛋白减弱能力结合在一起
5. Synthesis and biochemical evaluation of multifunctional acetylcholinesterase inhibitor hybrids for treatment of Alzheimer's disease. [D] . Eckroat, Todd J. 2014

机译：多功能乙酰胆碱酯酶抑制剂杂种的合成及其生化评估，用于治疗阿尔茨海默氏病。
6. Novel ligand-based docking; molecular dynamic simulations; and absorption distribution metabolism and excretion approach to analyzing potential acetylcholinesterase inhibitors for Alzheimers disease [O] . Subramaniyan Vijayakumar, Palani Manogar, Srinivasan Prabhu, 2018

机译：基于配体的新型对接；分子动力学模拟；和吸收分布代谢和排泄方法来分析潜在的乙酰胆碱酯酶抑制剂对阿尔茨海默氏病的影响
7. Acetylcholinesterase Inhibitors for Alzheimer’s disease: Past, Present, and Potential Future [O] . Brandon Truong, Jose Quiroz, Ronny Priefer 2020

机译：阿尔茨海默病的乙酰胆碱酯酶抑制剂：过去，现在和潜在的未来

Acetylcholinesterase noncovalent inhibitors based on a polyamine backbone for potential use against Alzheimer's disease.

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