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首页> 外文期刊>Journal of neuro-oncology. >Frame-based stereotactic biopsy remains an important diagnostic tool with distinct advantages over frameless stereotactic biopsy.
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Frame-based stereotactic biopsy remains an important diagnostic tool with distinct advantages over frameless stereotactic biopsy.

机译：与无框立体定向活检相比，基于框的立体定向活检仍然是重要的诊断工具。

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Object: As the availability of image-guided surgical navigation systems has increased, the application of frame-based biopsy has declined at our institution, despite equivalent accuracy and safety. There are several cost issues separating the use of surgical navigation systems and stereotactic frames for simple biopsy which may have implications in this era of health care cost control. We retrospectively reviewed the UCSF experience with stereotactic brain biopsy from a 9 year period. Methods: Data were collected for 213 consecutive stereotactic brain biopsies performed at UCSF (139 frame-based and 74 frameless). There were no significant differences between the frame-based and frameless biopsy groups with regard to patient demographics, overall histopathology, proportion of nondiagnostic biopsies, or incidence of complications. General anesthesia was used for 9 (6%) and 70 (95%) of the frame-based and frameless biopsy cases, respectively. Frame-based biopsies required a mean of 114 +/- 3 min of operating room time, while frameless biopsies required 185 +/- 6 min (P < 0.0001). For patients admitted to our neurosurgery service who underwent frame-based (n=110) or frameless (n=52) biopsy within 24 h of admission, the mean lengths of hospital stay were 1.8 +/- 0.2 and 3.2 +/- 0.6 days, respectively (P=0.007). Conclusion: Frame-based and frameless stereotactic biopsy approaches were equally effective at providing a tissue diagnosis with minimum morbidity and mortality. The frame-based approach, however, required significantly less anesthesia resources, less operating room time and shorter hospital stays, and thus should still be considered a first-line approach for stereotactic brain biopsy.
机译：目的：随着影像引导手术导航系统可用性的提高，尽管准确性和安全性相当，但在我们机构中，基于框架的活检的应用却有所减少。将手术导航系统和立体定向框架用于简单活检分开存在几个成本问题，这可能在这个医疗保健成本控制时代中产生影响。我们回顾性地回顾了UCSF自9年以来进行的立体定向脑活检的经验。方法：收集了在UCSF进行的213次连续立体定向脑活检的数据（139帧为基础，74帧为无帧）。基于框架的和无框架的活检组之间在患者人口统计学，整体组织病理学，非诊断性活检的比例或并发症发生率方面无显着差异。全身麻醉分别用于基于框架和无框架活检病例的9（6％）和70（95％）。框架活检平均需要114 +/- 3分钟的手术室时间，而无框架活检则需要185 +/- 6分钟（P <0.0001）。对于接受我们神经外科服务的患者，在入院后24小时内进行了基于框架的（n = 110）或无框架（n = 52）活检，平均住院时间为1.8 +/- 0.2天和3.2 +/- 0.6天，分别为（P = 0.007）。结论：基于框架和无框架的立体定向活检方法在提供最低发病率和死亡率的组织诊断方面同样有效。然而，基于框架的方法需要的麻醉资源明显更少，手术室时间更少，住院时间更短，因此仍应被视为立体定向脑活检的一线方法。

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