Improved oral bioavailability of glyburide by a self-nanoemulsifying drug delivery system

Liu Hongzhuo; Shang Kuimao; Liu Weina; Leng Donglei; Li Ran; Kong Ying; Zhang Tianhong

首页> 外文期刊>Journal of Microencapsulation: Microcapsules Liposomes Nanoparticles Microcells Microspheres >Improved oral bioavailability of glyburide by a self-nanoemulsifying drug delivery system

【24h】

Improved oral bioavailability of glyburide by a self-nanoemulsifying drug delivery system

机译：通过自纳米乳化药物递送系统改善格列本脲的口服生物利用度

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Aim: The present study aimed at the development and characterisation of self-nanoemulsifying drug delivery system (SNEDDS) to improve the oral bioavailability of poorly soluble glyburide. Methods: The solubility of glyburide was determined in various oils, surfactants and co-surfactants which were grouped into two different combinations to construct ternary phase diagrams. The formulations were evaluated for emulsification time, droplet size, zetapotential, electrical conductivity and stability of nanoemulsions.

机译：目的：本研究旨在开发和表征自纳米乳化药物递送系统（SNEDDS），以改善难溶性格列本脲的口服生物利用度。方法：测定格列本脲在各种油，表面活性剂和助表面活性剂中的溶解度，将这些油分为两种不同的组合以构建三元相图。评价制剂的乳化时间，液滴尺寸，ζ电位，电导率和纳米乳剂的稳定性。

著录项

来源
《Journal of Microencapsulation: Microcapsules Liposomes Nanoparticles Microcells Microspheres》 |2014年第8期|共7页
作者
Liu Hongzhuo; Shang Kuimao; Liu Weina; Leng Donglei; Li Ran; Kong Ying; Zhang Tianhong;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类药剂学;
关键词
Bioavailability; glyburide; in vitro release; self-nanoemulsifying drug delivery system;

机译：生物利用度;格列本脲;体外释放;自纳米乳化给药系统;

相似文献

外文文献
中文文献
专利

1. Improved oral bioavailability of glyburide by a self-nanoemulsifying drug delivery system [J] . Liu Hongzhuo, Shang Kuimao, Liu Weina, Journal of Microencapsulation: Microcapsules Liposomes Nanoparticles Microcells Microspheres . 2014,第1a8期

机译：通过自纳米乳化药物递送系统改善格列本脲的口服生物利用度
2. Design of absorption enhancer containing self-nanoemulsifying drug delivery system (SNEDDS) for curcumin improved anti-cancer activity and oral bioavailability [J] . Kanwal Tasmina, Saifullah Salim, Rehman Jawad Ur, Journal of Molecular Liquids . 2021,第1期

机译：含有自纳中乳化药物输送系统（SNEDDS）的吸收增强剂的设计，用于姜黄素改善抗癌活性和口服生物利用度
3. Self-nanoemulsifying drug delivery system of nabumetone improved its oral bioavailability and anti-inflammatory effects in rat model [J] . Chaudhary Sadaf, Aqil Mohd, Sultana Yasmin, Journal of drug delivery science and technology . 2019,第期

机译：Nabumetone的自纳乳化药物递送系统改善了大鼠模型中的口服生物利用度和抗炎作用
4. Novel Self-nanoemulsifying Drug Delivery System (SNEDDS) for Oral Delivery ofEssential Oil: Formulation and Bioavailability Study [C] . Y. Zheng, Y Zhao, C.G. Wang, . 2009

机译：口服精油的新型自乳化药物输送系统（SNEDDS）：制剂和生物利用度研究
5. Development of a self-nanoemulsifying drug delivery system for oral delivery of beta-lactamase. [D] . Venkata Ramana Rao, Sripriya. 2008

机译：开发了用于口服β-内酰胺酶的自纳米乳化药物递送系统。
6. A novel solid self-nanoemulsifying drug delivery system (S-SNEDDS) for improved stability and oral bioavailability of an oily drug 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol [O] . Kyeong Soo Kim, Eun Su Yang, Dong Shik Kim, 2017

机译：一种新型固体自纳中乳化药物递送系统（S-SNEDDS）用于改善油性药物的稳定性和口服生物利用度1-palmItoyl-2-丙烯酰基-3-乙酰基-RAC-甘油
7. Novel Solid Self-Nanoemulsifying Drug Delivery System (S-SNEDDS) for Oral Delivery of Olmesartan Medoxomil: Design, Formulation, Pharmacokinetic and Bioavailability Evaluation [O] . Ali Nasr, Ahmed Gardouh, Mamdouh Ghorab 2016

机译：用于口服奥美沙坦酯的新型固体自纳米乳化药物传递系统（s-sNEDDs）：设计，制剂，药代动力学和生物利用度评估

Improved oral bioavailability of glyburide by a self-nanoemulsifying drug delivery system

摘要

著录项

相似文献

相关主题

期刊订阅