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首页> 外文期刊>Journal of neurology >Relationship between lesion location and the outcome of pallidotomy for Parkinson's disease.
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Relationship between lesion location and the outcome of pallidotomy for Parkinson's disease.

机译：病变位置与帕金森病苍白球切开术结局之间的关系。

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摘要

The relationships between lesion location and clinical outcome following posteroventral pallidotomy for Parkinson's disease were studied. Forty-four patients were operated forty-six times and studied with neurological and psychological examinations before and after pallidotomy. Lesion location was confirmed using films with a coagulation electrode which were X-rayed during the operation. Changes of intelligence were observed in the patients with anteromedial lesions. Wearing-off phenomenon in four patients and dopa-induced dyskinesia in three patients were not improved following pallidotomy in twenty patients with severe wearing-off and dyskinesia. Lesions in the patients with no improvement of wearing off were located more lateral and those in the patients with sustained severe dyskinesia were located more dorsal in the internal part of the globus pallidus. It may be concluded that clinical outcome is related to lesion location.
机译：研究了帕金森氏病后腹苍白球切开术后病变部位与临床结局之间的关系。四十四例患者接受了四十六次手术，并在苍白球切开术之前和之后接受了神经和心理检查。使用具有凝结电极的薄膜在手术过程中对其进行X线检查，以确认病变部位。在患有前内侧病变的患者中观察到智力的变化。四名患者发生苍白球切开术后，四名患者的穿脱现象和多巴诱发的运动障碍并未得到改善，其中二十名患有严重的穿脱和运动障碍。磨损没有改善的患者的病灶位于外侧，而持续严重运动障碍的患者的病灶位于苍白球内侧。可以得出结论，临床结果与病变位置有关。

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