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首页> 外文期刊>Journal of Perinatal Medicine >Evaluation of serum boron levels and lipid profile in pregnancies with or without gestational diabetes
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Evaluation of serum boron levels and lipid profile in pregnancies with or without gestational diabetes

机译:妊娠糖尿病或非妊娠糖尿病患者血清硼水平和血脂水平的评估

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Aims: Animal research has demonstrated that boron has effects on triglycerides and glucose and may act as a metabolic regulator in several enzymatic systems. Gestational diabetes mellitus (GDM) is a prevalent obstetrical complication and the lack of data on maternal status of boron in normal/diabetic pregnancies, prompted us to undertake this study. Methods: Maternal blood samples were collected during screening and diagnosis of GDM at 24 - 28 weeks. Serum lipids (total cholesterol, high-density cholesterol, low density cholesterol, triglycerides, lipoprotein-a, apolipoprotein-A-I and apolipoprotein-B) and boron levels were determined. Fifteen non-GDM and 19 GDM women constituted the study population. Results: The mean age was 30.1 ± 5 years. The median boron levels were 15.2 μ g/L (0.0152 ppm; range, 8.4 - 25.4 μ g/L). When GDM and non-GDM cases were compared for age, gravidity, parity, lipid profiles and serum boron levels, no significant differences were found (P > 0.05). No correlation was found between lipids and boron levels. Conclusion: This preliminary study contributes to the limited information about the metabolic aspects of boron. Considering the evidence that boron acts as a regulator of energy substrate utilization, the effect of dietary boron on glucose metabolism deserves further research.
机译:目的:动物研究表明,硼对甘油三酸酯和葡萄糖有影响,并可能在几种酶系统中充当代谢调节剂。妊娠糖尿病(GDM)是一种普遍的产科并发症,由于缺乏正常/糖尿病孕妇中硼的母体状况的数据,促使我们进行了这项研究。方法:在24至28周的GDM筛查和诊断过程中收集母体血液样本。测定血清脂质(总胆固醇,高密度胆固醇,低密度胆固醇,甘油三酸酯,脂蛋白-a,载脂蛋白-A-I和载脂蛋白-B)和硼水平。 15名非GDM妇女和19名GDM妇女组成了研究人群。结果:平均年龄为30.1±5岁。硼中位数为15.2μg / L(0.0152 ppm;范围8.4-25.4μg / L)。当比较GDM和非GDM病例的年龄,妊娠率,胎次,血脂和血清硼水平时,没有发现显着差异(P> 0.05)。在脂质和硼水平之间未发现相关性。结论:这项初步研究有助于有关硼代谢方面的有限信息。考虑到硼可作为能量底物利用的调节剂,饮食硼对葡萄糖代谢的影响值得进一步研究。

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