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首页> 外文期刊>Journal of perinatology: Official journal of the California Perinatal Association >Diffuse basal ganglia or thalamus hyperechogenicity in preterm infants.
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Diffuse basal ganglia or thalamus hyperechogenicity in preterm infants.

机译：早产儿弥漫性基底神经节或丘脑高回声。

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OBJECTIVE: To determine the incidence and factors associated with diffuse basal ganglia or thalamus hyperechogenicity (BGTH) in preterm infants. STUDY DESIGN: (1) Review of serial neurosonograms among neonates with gestational age (GA) <34 weeks born at Weiler Hospital during a 21-month period; (2) Color Doppler flow imaging; (3) Case-control study using GA group-matched controls; and (4) Blind reading of CT scans or MRIs in patients with BGTH. RESULTS: Among 289 infants, 24 (8.3%) had diffuse BGTH. Color Doppler flow imaging was normal in nine patients. The incidence of diffuse BGTH was inversely related to GA (P<0.01). Logistic regression (n=96) showed that diffuse BGTH was significantly associated with requirement of high-frequency oscillation (HFO) (P=0.031), severe intraventricular hemorrhage (IVH) (P=0.004), hypotension requiring vasopressors (P=0.040), hypoglycemia (P=0.031) and male gender (P=0.014). Most patients with diffuse BGTH had normal basal ganglia and thalamus on CT/MRI, one had a hemorrhage, and one had an ischemic infarction. CONCLUSIONS: In our series, diffuse BGTH occurred in 8.3%, and was associated with factors similar to those previously reported. In contrast, several series have reported almost exclusively linear or punctuate hyperechoic foci, corresponding to hyperechogenicity of the lenticulostriate vessels. Our data provide further evidence to suggest that diffuse BGTH and hyperechogenicity of the lenticulostriate vessels are two different entities. Additional studies are required to determine the long-term significance of diffuse BGTH.
机译：目的：确定早产儿弥漫性基底神经节或丘脑高回声性（BGTH）的发生率和相关因素。研究设计：（1）在21个月内于Weiler医院出生的胎龄（GA）<34周的新生儿中进行系列超声检查; （2）彩色多普勒血流显像; （3）使用与GA组匹配的对照进行病例对照研究; （4）BGTH患者的CT扫描或MRI盲读。结果：在289名婴儿中，有24名（8.3％）患有弥漫性BGTH。 9例患者的彩色多普勒血流显像正常。弥漫性BGTH的发生与GA呈负相关（P <0.01）。 Logistic回归分析（n = 96）显示弥漫性BGTH与高频振荡（HFO）（P = 0.031），严重脑室内出血（IVH）（P = 0.004），需要降压药（P = 0.040）的血压显着相关，低血糖（P = 0.031）和男性（P = 0.014）。大多数弥漫性BGTH患者的CT / MRI表现为基底神经节和丘脑正常，其中一名患者出血，一名缺血性梗塞。结论：在我们的系列中，弥漫性BGTH发生率为8.3％，并且与先前报道的因素相似。相比之下，几个系列报道了几乎全部是线性或点状的高回声灶，这与小齿状血管的超回声性相对应。我们的数据提供了进一步的证据，表明扁豆状血管的弥漫性BGTH和高回声性是两个不同的实体。需要进行其他研究以确定弥漫性BGTH的长期意义。

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