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首页> 外文期刊>Journal of perinatology: Official journal of the California Perinatal Association >Movement, imaging and neurobehavioral assessment as predictors of cerebral palsy in preterm infants.
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Movement, imaging and neurobehavioral assessment as predictors of cerebral palsy in preterm infants.

机译：运动，成像和神经行为评估可预测早产儿脑瘫。

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OBJECTIVE: To study the relative efficacy of three early predictors of cerebral palsy. METHOD: One Hundred and thirty infants with birth weight <1500 g were recruited. Video recordings of spontaneous general movements were made at 36 and 52 weeks postconceptional age. Magnetic resonance imaging and the neurobehavioral assessment of the preterm infant were done at 36 weeks postconceptional age. Follow-up neurological examination and Bayley assessments were made at 18 months corrected age to make early identification of cerebral palsy. RESULTS: Magnetic resonance imaging gave the best specificity and accuracy of 91 and 84% respectively. General movements at 52 weeks showed an improved specificity and accuracy over performance at 36 weeks postconceptional age. The negative predictive value for all methods tested was between 90 and 97%. Combining the results of magnetic resonance imaging and the neurobehavioral assessment improved the sensitivity of prediction to 80%, suggesting that a holistic approach toearly detection of cerebral lesions is preferable to a single test. CONCLUSIONS: The majority of infants who appeared to behave within normal limits and exhibit normal brain structure in the newborn period were classified as neurologically intact at follow-up.
机译：目的：研究三种早期预测脑瘫的相对疗效。方法：招募一百三十个出生体重<1500 g的婴儿。在受孕后36和52周进行自发性一般运动的视频记录。早产儿在孕36周时进行了磁共振成像和神经行为评估。在矫正年龄的18个月时进行随访神经系统检查和Bayley评估，以及早发现脑瘫。结果：磁共振成像的最佳特异性和准确性分别为91％和84％。在受孕后36周，一般运动在52周时表现出的特异性和准确性较其表现有所提高。所有测试方法的阴性预测值在90％至97％之间。磁共振成像和神经行为评估的结果相结合，将预测的敏感性提高到80％，这表明采用整体方法及早检测脑部病变要优于单一测试。结论：在随访期间，大多数表现在正常范围内并表现出正常脑结构的婴儿被归类为神经学完整的。

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