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首页> 外文期刊>Journal of psychopharmacology >Single doses of Panax ginseng (G115) reduce blood glucose levels and improve cognitive performance during sustained mental activity.
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Single doses of Panax ginseng (G115) reduce blood glucose levels and improve cognitive performance during sustained mental activity.

机译：人参（G115）的单剂量可降低持续的精神活动期间的血糖水平并改善认知能力。

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Single doses of the traditional herbal treatment Panax ginseng have recently been shown to elicit cognitive improvements in healthy young volunteers. The mechanisms by which ginseng improves cognitive performance are not known. However, they may be related to the glycaemic properties of some Panax species. Using a double-blind, placebo-controlled, balanced crossover design, 30 healthy young adults completed a 10 min test battery at baseline, and then six times in immediate succession commencing 60 min after the day's treatment (placebo, 200mg G115 or 400mg G115). The 10 min battery comprised a Serial Threes subtraction task (2 min); a Serial Sevens task (2 min); a Rapid Visual Information Processing task (5 min); then a 'mental fatigue' visual analogue scale. Blood glucose was measured prior to each day's treatment, and before, during and after the post-dose completions of the battery. Both the 200mg and 400mg treatments led to significant reductions in blood glucose levels at all three post-treatment measurements (p 0.005 in all cases). The most notable behavioural effects were associated with 200mg of ginseng and included significantly improved Serial Sevens subtraction task performance and significantly reduced subjective mental fatigue throughout all (with the exception of one time point in each case) of the post-dose completions of the 10 min battery (p 0.05). Overall these data suggest that Panax ginseng can improve performance and subjective feelings of mental fatigue during sustained mental activity. This effect may be related to the acute gluco-regulatory properties of the extract.
机译：最近已显示单剂传统草药人参能在健康的年轻志愿者中引起认知改善。人参改善认知能力的机制尚不清楚。但是，它们可能与某些人参物种的血糖特性有关。使用双盲，安慰剂对照，平衡的交叉设计，30名健康的年轻人在基线时完成了10分钟的测试电池，然后在一天的治疗后60分钟开始连续六次连续测试（安慰剂，200mg G115或400mg G115） 。 10分钟的电池包括连续三人减法任务（2分钟）;连续七人制任务（2分钟）;快速视觉信息处理任务（5分钟）;然后是“精神疲劳”视觉模拟量表。在每天的治疗之前，在给药后完成电池之前，期间和之后测量血糖。在所有三个治疗后测量中，200mg和400mg治疗均导致血糖水平显着降低（在所有情况下均为0.005）。最显着的行为影响是与200mg人参有关，包括在给药后10分钟的所有完成过程中（除每种情况下的一个时间点之外），所有人的七连冠减法任务表现显着改善，主观精神疲劳显着降低。电池（p 0.05）。总体而言，这些数据表明人参可以在持续的精神活动中改善精神疲劳的表现和主观感觉。该作用可能与提取物的急性葡萄糖调节特性有关。

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