Prenatal screening for open neural tube defects.

Canick JA; Kellner LH; Bombard AT

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Prenatal screening for open neural tube defects.

机译：产前筛查开放性神经管缺损。

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The era of prenatal screening for serious birth defects began in the 1970s with the discovery that amniotic fluid and maternal serum levels of alpha-fetoprotein (AFP) were increased in pregnancies affected by fetal open neural tube defects. Since then, prenatal screening has become a part of routine obstetric care. In this article, the use of AFP in prenatal screening for open neural tube defects is discussed in the context of the laboratory and the laboratory's interactions with the practicing obstetrician.

机译：严重的先天缺陷的产前筛查时代始于1970年代，这一发现发现，受胎儿开放性神经管畸形影响的孕妇的羊水和母体血清甲胎蛋白（AFP）水平会升高。从那时起，产前筛查已成为常规产科护理的一部分。在本文中，将在实验室的背景下以及实验室与执业产科医生的互动中讨论AFP在产前筛查开放性神经管缺损中的应用。

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来源
《Clinics in laboratory medicine》 |2003年第2期|共11页
作者
Canick JA; Kellner LH; Bombard AT;
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正文语种 eng
中图分类临床医学;
关键词
Aspects of disease screening; defects; Neural tube; prenatal; Prenatal brand of multivitamin;

机译：疾病筛查;缺陷;神经管;产前;多种维生素的产前品牌;

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专利

1. Prenatal screening and diagnosis of neural tube defects. [J] . Cameron M, Moran P Prenatal Diagnosis . 2009,第4期

机译：产前筛查和诊断神经管缺陷。
2. Prenatal biochemical screening for neural tube defects. [J] . Muller F Child's nervous system: ChNS : official journal of the International Society for Pediatric Neurosurgery . 2003,第7a8期

机译：产前生化检查神经管缺陷。
3. Prenatal biochemical screening for neural tube defects. [J] . Muller F Child's nervous system: ChNS : official journal of the International Society for Pediatric Neurosurgery . 2003,第7a8期

机译：产前生化检查神经管缺陷。
4. Mobile urinalysis for maternal screening: Frugal medical screening solution and patient database to aid in prenatal healthcare for expecting mothers in the developing world [C] . Joseph Neumeyer, Jacob Prince, Amy Miller, IEEE Global Humanitarian Technology Conference . 2016

机译：用于孕妇筛查的移动尿液分析：节俭医疗筛查解决方案和患者数据库，可帮助发展中国家的准妈妈进行产前保健
5. Establishing Caenorhabditis elegans as a model for neural tube defects. [D] . King, Chelle. 2010

机译：建立秀丽隐杆线虫作为神经管缺陷的模型。
6. Hazards of prenatal detection of neural tube defects. [O] . P. F. Hall 1979

机译：产前检测神经管缺陷的危险。
7. Alpha-fetoprotein and the prenatal detection of neural tube defects. [O] . Milunsky, A 1979

机译：甲胎蛋白和产前检测神经管缺陷。
8. Epidemiologic Aspects of Neural Tube Defects in the United States: Changing Concepts and Their Importance for Screening and Prenatal Diagnostic Programs [R] . Sever, L. E., Strassburg, M. A. 1983

机译：美国神经管缺陷的流行病学方面：改变概念及其对筛查和产前诊断程序的重要性

Prenatal screening for open neural tube defects.

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