Prenatal biochemical screening for neural tube defects.

Muller F

首页> 外文期刊>Child's nervous system: ChNS : official journal of the International Society for Pediatric Neurosurgery >Prenatal biochemical screening for neural tube defects.

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Prenatal biochemical screening for neural tube defects.

机译：产前生化检查神经管缺陷。

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INTRODUCTION: Neural tube defects (NTDs) can be considered as a folate deficiency disorder. The prevalence of NTDs ranges from about 0.5 to 6 in 1,000 births. DISCUSSION: Two steps can be distinguished in biochemical screening for NTDs: 1. Screening in the general population, which is based on two complementary methods, maternal serum AFP screening and ultrasound screening; 2. Screening in a high-risk group, which requires fetal scanning by an expert sonographer. CONCLUSION: Amniocentesis for acetylcholinesterase electrophoresis is indicated when sonographic scans are difficult to interpret.

机译：简介：神经管缺损（NTD）可被视为叶酸缺乏症。每1000名婴儿中NTD的患病率约为0.5至6。讨论：NTDs的生化筛查可以分为两个步骤：1.在普通人群中进行筛查，这是基于两种补充方法，即母体血清AFP筛查和超声筛查; 2.在高危人群中进行筛查，这需要由超声检查专家进行胎儿扫描。结论：当超声检查难以解释时，建议进行乙酰胆碱酯酶电泳的羊膜穿刺术。

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《Child's nervous system: ChNS : official journal of the International Society for Pediatric Neurosurgery》 |2003年第8期|共3页
作者
Muller F;
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正文语种 eng
中图分类儿童神经病;
关键词
Biochemistry; Mass Screening; Neural Tube Defects; Prenatal Diagnosis; 生物化学; 普查; 神经管缺损; 产前诊断;

机译：Biochemistry;Mass Screening;Neural Tube Defects;Prenatal Diagnosis;生物化学;普查;神经管缺损;产前诊断;

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1. Prenatal biochemical screening for neural tube defects. [J] . Muller F Child's nervous system: ChNS : official journal of the International Society for Pediatric Neurosurgery . 2003,第7a8期

机译：产前生化检查神经管缺陷。
2. Prenatal screening and diagnosis of neural tube defects. [J] . Cameron M, Moran P Prenatal Diagnosis . 2009,第4期

机译：产前筛查和诊断神经管缺陷。
3. Prenatal screening for open neural tube defects. [J] . Canick JA, Kellner LH, Bombard AT Clinics in laboratory medicine . 2003,第2期

机译：产前筛查开放性神经管缺损。
4. The second trimester screening for fetal chromosomal aneuploidy and Open neural tube defects [C] . HU Ya-li International Forum on Progress on Post-Genome Technologies(5'IFPT); 20070910-11; Suzhou(CN) . 2007

机译：孕中期筛查胎儿染色体非整倍性和开放性神经管缺损
5. Establishing Caenorhabditis elegans as a model for neural tube defects. [D] . King, Chelle. 2010

机译：建立秀丽隐杆线虫作为神经管缺陷的模型。
6. Hazards of prenatal detection of neural tube defects. [O] . P. F. Hall 1979

机译：产前检测神经管缺陷的危险。
7. Alpha-fetoprotein and the prenatal detection of neural tube defects. [O] . Milunsky, A 1979

机译：甲胎蛋白和产前检测神经管缺陷。
8. Epidemiologic Aspects of Neural Tube Defects in the United States: Changing Concepts and Their Importance for Screening and Prenatal Diagnostic Programs [R] . Sever, L. E., Strassburg, M. A. 1983

机译：美国神经管缺陷的流行病学方面：改变概念及其对筛查和产前诊断程序的重要性

Prenatal biochemical screening for neural tube defects.

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